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Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe
Dissertation (MSc)--University of Pretoria, 2018.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2019
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| _version_ | 1867613551935356928 |
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| access_status_str | Open Access |
| author2 | Crafford, Jan Ernst |
| author_browse | Crafford, Jan Ernst |
| author_facet | Crafford, Jan Ernst |
| collection | Thesis |
| dc_rights_str_mv | © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc)--University of Pretoria, 2018. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/70495 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:37:57.427Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/70495 Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe Crafford, Jan Ernst u16391218@tuks.co.za Maritz-Olivier, Christine Spargo, Reverend Moregood UCTD Dissertation (MSc)--University of Pretoria, 2018. Cattle ticks from the genus Rhipicephalus are hematophagous ectoparasites of great veterinary and economic importance. Currently, the main method for managing ticks and tick-borne diseases is the application of chemical acaricides. Development of resistance to these acaricides however poses a threat to the livestock sector globally, including Zimbabwe. Surveillance for acaricide resistance is essential for controlling tick populations via early intervention with an active compound to which there is no resistance in the field. In this study the allele frequencies that occur in genes linked to pyrethroid and amitraz resistance, namely the voltage-gated sodium channel and the octopamine/tyramine receptor were investigated. Specific nucleotide polymorphisms (SNPs) of Rhipicephalus spp in these genes were analysed from 18 communal dip tanks in the eastern parts of Zimbabwe. No SNPs were identified in the domain II region of the voltage-gated sodium channel gene associated with pyrethroid resistance. Resistant alleles associated with amitraz resistance in both R. decoloratus and R. microplus tick populations were observed. The level of acaricide resistance was subsequently calculated and solutions for improved acaricide resistance control are discussed. Veterinary Tropical Diseases MSc Unrestricted 2019-07-08T09:46:35Z 2019-07-08T09:46:35Z 2019/04/04 2018 Dissertation Spargo, RM 2018, Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/70495> A2019 http://hdl.handle.net/2263/70495 en © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe |
| title | Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe |
| title_full | Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe |
| title_fullStr | Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe |
| title_full_unstemmed | Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe |
| title_short | Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe |
| title_sort | allele frequencies of acaricide resistance associated specific nucleotide polymorphisms in rhipicephalus microplus and rhipicephalus decoloratus in manicaland zimbabwe |
| topic | UCTD |
| url | http://hdl.handle.net/2263/70495 |