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Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial

Dissertation (MSc Dent)--University of Pretoria, 2020.

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Other Authors: Marnewick, J.C. (Johan)
Format: Thesis
Language:English
Published: University of Pretoria 2020
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access_status_str Open Access
author2 Marnewick, J.C. (Johan)
author_browse Marnewick, J.C. (Johan)
author_facet Marnewick, J.C. (Johan)
collection Thesis
dc_rights_str_mv © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Dissertation (MSc Dent)--University of Pretoria, 2020.
format Thesis
id oai:repository.up.ac.za:2263/75860
institution University of Pretoria (South Africa)
language English
last_indexed 2026-06-10T12:40:08.978Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher University of Pretoria
publisherStr University of Pretoria
record_format dspace
source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/75860 Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial Marnewick, J.C. (Johan) jantand@absamail.co.za Postma, Thomas Corne Olivier, Johannes Petrus Jacobus UCTD SDG-03: Good health and well-being SDG-17: Partnerships for the goals Dissertation (MSc Dent)--University of Pretoria, 2020. Aim: With dental implant treatment having evolved into a very regularly applied treatment modality, post-extraction grafting of extraction sockets with DFDBA in an effort to anticipate and pre-empt post-extraction bone loss has become common practice – clinically known as ridge preservation procedures. The aim of this study was however to histologically determine the quality of bone available for implant placement using DFDBA as grafting material in combination with a resorbable collagen membrane, compared to bone in extraction sockets that were left to heal naturally. Method: Twenty sites were identified from eight patients requiring replacement of two or more extracted teeth by means of dental implant supported structures, on contralateral sides of the same jaw. They received DFDBA grafting of the socket on one side and no grafting on the contralateral side at the time of extraction. When implants were placed 16 – 20 weeks later, core samples of bone from these sites were first harvested by means of a trephine drill and those samples were processed and examined histologically to determine which of these sites displayed better quality of bone. Results: One patient’s samples could not be utilised. Comparing the samples of the remaining nine non-grafted to nine grafted extraction sites, the difference in the calculated percentages of trabecular bone and collagen as well as the numbers of osteocytes, inflammatory cells and blood vessels were statistically insignificant. Conclusion: The results of the study indicate that statistically there are no significant histological differences between DFDBA-grafted and non-grafted sockets. em2026 Periodontics and Oral Medicine MSc Dent Unrestricted SDG-03: Good health and well-being SDG-17: Partnerships for the goals 2020-08-24T07:30:01Z 2020-08-24T07:30:01Z 2020 2020 Dissertation *Olivier, JPJ 2020, Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial, MScDent Dissertation, University of Pretoria, Pretoria S2020 http://hdl.handle.net/2263/75860 en © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle UCTD
SDG-03: Good health and well-being
SDG-17: Partnerships for the goals
Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial
title Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial
title_full Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial
title_fullStr Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial
title_full_unstemmed Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial
title_short Histologic healing following tooth extraction with socket grafting using demineralised freeze-dried bone allograft (DFDBA), compared to undisturbed normal healing in humans: a randomised controlled clinical trial
title_sort histologic healing following tooth extraction with socket grafting using demineralised freeze dried bone allograft dfdba compared to undisturbed normal healing in humans a randomised controlled clinical trial
topic UCTD
SDG-03: Good health and well-being
SDG-17: Partnerships for the goals
url http://hdl.handle.net/2263/75860