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In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers
Thesis (PhD (Dietetics))--University of Pretoria, 2019.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2020
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| _version_ | 1867613501878435840 |
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| access_status_str | Open Access |
| author2 | Wenhold, F.A.M. (Friedeburg Anna Maria) |
| author_browse | Wenhold, F.A.M. (Friedeburg Anna Maria) |
| author_facet | Wenhold, F.A.M. (Friedeburg Anna Maria) |
| collection | Thesis |
| dc_rights_str_mv | © 2020 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Thesis (PhD (Dietetics))--University of Pretoria, 2019. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/76875 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:37:09.691Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/76875 In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers Wenhold, F.A.M. (Friedeburg Anna Maria) kemridge@absamail.co.za Nakwa, Firdose Kemp, Johanna Elizabeth UCTD Preterm infant growth human milk fortifier Health sciences theses SDG-03 SDG-03: Good health and well-being Health sciences theses SDG-17 SDG-17: Partnerships for the goals Thesis (PhD (Dietetics))--University of Pretoria, 2019. The protein content of the only human milk fortifier available in South Africa was increased in 2017. The Original fortifier (OF) and the Reformulated fortifier (RF) provided similar energy. This study aimed to prospectively compare in-hospital growth during the intermediate stage of nutrition support of very low birth weight (VLBW) preterm infants receiving human milk fortified with these two formulations in a tertiary South African hospital. Intake of VLBW infants receiving exclusively human milk plus one of two fortifiers (OF 0.2gprotein/g powder; RF 0.4gprotein/g powder) was calculated. Change in Z-scores (Fenton, 2013) from start to end of fortification of weight, length and head circumference (HC) for age was calculated as primary outcomes. Additionally, weight gain velocity (g/kg/d) and gain in length and HC (cm/wk) were calculated. Fifty eight infants (52% female; gestational age: 30±2wk; birth weight: 1215±187g) received OF (2016 to 2017) and 59 infants (56% female; gestational age: 29±2wk; birth weight 1202±167g) received RF (2017 to 2018) for 15 days. Protein intake of RF (3.7±0.4g/kg/d) was significantly higher (p<0.001) than of OF (3.4±0.2g/kg/d). Protein-to-energy ratio of RF (2.6±0.2) was significantly higher (p<0.001) than of OF (2.3±0.1g/100kcal). No adverse effects were noted. In both groups Z-scores of weight and length dropped; Z-scores for HC showed slight improvements. There were no significant differences between the two groups in terms of Z-scores, weight gain velocity, length gain or HC gain. Analysed human milk from preterm infants’ mothers’ protein levels was higher than published values. In-hospital growth was not statistically different between groups, even though calculated protein intake and protein-to-energy ratio were significantly higher in RF group. em2025 Human Nutrition PhD (Dietetics) Unrestricted SDG-03: Good health and well-being SDG-17: Partnerships for the goals 2020-11-04T15:10:14Z 2020-11-04T15:10:14Z 20/04/17 2020 Thesis Kemp, JE 2020, In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers, PhD (Dietetics) Thesis, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/76875> A2020 http://hdl.handle.net/2263/76875 en © 2020 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Preterm infant growth human milk fortifier Health sciences theses SDG-03 SDG-03: Good health and well-being Health sciences theses SDG-17 SDG-17: Partnerships for the goals In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers |
| title | In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers |
| title_full | In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers |
| title_fullStr | In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers |
| title_full_unstemmed | In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers |
| title_short | In-hospital growth of very low birth weight preterm infants : comparative effectiveness of two human milk fortifiers |
| title_sort | in hospital growth of very low birth weight preterm infants comparative effectiveness of two human milk fortifiers |
| topic | UCTD Preterm infant growth human milk fortifier Health sciences theses SDG-03 SDG-03: Good health and well-being Health sciences theses SDG-17 SDG-17: Partnerships for the goals |
| url | http://hdl.handle.net/2263/76875 |