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Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review

Dissertation (MA (Speech-Language Pathology))--University of Pretoria, 2021.

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Other Authors: Kruger, Esedra
Format: Thesis
Language:English
Published: University of Pretoria 2021
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access_status_str Open Access
author2 Kruger, Esedra
author_browse Kruger, Esedra
author_facet Kruger, Esedra
collection Thesis
dc_rights_str_mv © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Dissertation (MA (Speech-Language Pathology))--University of Pretoria, 2021.
format Thesis
id oai:repository.up.ac.za:2263/80710
institution University of Pretoria (South Africa)
language English
last_indexed 2026-06-10T12:40:40.078Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher University of Pretoria
publisherStr University of Pretoria
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source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/80710 Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review Kruger, Esedra kruppa.kayla.kayla@gmail.com Van der Linde, Jeannie Vorster, Carlien Kruppa, Kayla UCTD Speech-language pathology (SLP) Cleft lip and/or palate (CL/P) Systematic review Dissertation (MA (Speech-Language Pathology))--University of Pretoria, 2021. Background: Cleft lip and/or palate (CL/P) is a complex, heterogeneous disorder which occurs due to the interplay between environmental and biological risk factors. Individuals in lower-middle-income countries (LMICs) are exposed to a multitude of risk factors resulting in a greater occurrence of CL/P. Research and knowledge of which risk factors are associated with CL/P in LMICs may aid health care professionals such as speech-language therapists in low-income countries in the early identification of at-risk infants. Objective: To identify and review published data on the risks associated with CL/P in LMICs. Design: A systematic review of literature was performed on electronic databases using the PRISMA-P. Literature on risks associated with CL/P in LMICs, from 2010 to 2020 was included. Results: Seventeen studies met the inclusion criteria. All studies adopted an observational study design. Biological and environmental risks were identified. Maternal and paternal age (n=7) and low socioeconomic status (n=5) were the most prominently associated environmental risk factors. Regarding biological risk factors, a strong association was identified between family history of cleft (n=7) and CL/P occurrence. Conclusion: Environmental risk factors are now being investigated more than biological risk factors in LMICs, hindering health care workers in the early identification (EI) of the possible cumulative effects of risks in CL/P. Contextually-relevant tools are recommended to promote the EI of at-risk infants. Speech-Language Pathology and Audiology MA (Speech-Language Pathology) Unrestricted 2021-07-05T08:04:08Z 2021-07-05T08:04:08Z 2021-09 2021 Dissertation Kruppa, K 2021, Cleft lip and/or palate and associated risks in lower-middle-income countries: A systematic review, MA dissertation, University of Pretoria, Pretoria, viewed yymmdd http://hdl.handle.net/2263/80710 S2021 http://hdl.handle.net/2263/80710 en © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle UCTD
Speech-language pathology (SLP)
Cleft lip and/or palate (CL/P)
Systematic review
Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review
title Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review
title_full Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review
title_fullStr Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review
title_full_unstemmed Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review
title_short Cleft lip and/or palate and associated risks in lowermiddle-income countries : a systematic review
title_sort cleft lip and or palate and associated risks in lowermiddle income countries a systematic review
topic UCTD
Speech-language pathology (SLP)
Cleft lip and/or palate (CL/P)
Systematic review
url http://hdl.handle.net/2263/80710