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Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial

Thesis (PhD (Dietetics))--University of Pretoria, 2020.

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Other Authors: Wenhold, F.A.M. (Friedeburg Anna Maria)
Format: Thesis
Published: University of Pretoria 2021
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access_status_str Open Access
author2 Wenhold, F.A.M. (Friedeburg Anna Maria)
author_browse Wenhold, F.A.M. (Friedeburg Anna Maria)
author_facet Wenhold, F.A.M. (Friedeburg Anna Maria)
collection Thesis
dc_rights_str_mv © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Thesis (PhD (Dietetics))--University of Pretoria, 2020.
format Thesis
id oai:repository.up.ac.za:2263/82473
institution University of Pretoria (South Africa)
last_indexed 2026-06-10T12:39:33.363Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher University of Pretoria
publisherStr University of Pretoria
record_format dspace
source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/82473 Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial Wenhold, F.A.M. (Friedeburg Anna Maria) MacIntyre, Una Elizabeth Kotzé, Carla Kühn, Lizette UCTD Thesis (PhD (Dietetics))--University of Pretoria, 2020. Introduction The high prevalence and impact of dementia call for preventative measures, including application of an optimised diet. Omega 3 polyunsaturated fatty acids (PUFA) may influence the risk for developing dementia by supporting cardiovascular health and by decreasing inflammation. Research, particularly randomised controlled trials, studying a food-based approach that uses Omega 3 PUFA intake from foods such as fish to counteract dementia in low/middle income countries (LMIC), is lacking. Aim To determine the effect of supplementing diets of independently living, resource-limited elderly participants for 12 weeks with fish versus non-fish foods on cognition. Methods In a randomised controlled trial the usual diet of independently living elderly persons in a resource-limited retirement centre in urban South Africa was enhanced with contextappropriate foods i.e. canned baked beans, canola oil and peanut butter mimicking elements of the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet. Additionally, the intervention group received canned pilchards and fish spread (equivalent to a calculated daily intake of 2.2g Omega 3 PUFA) weekly compared to canned meatballs and texturised soya protein (meat substitute) received by the control group. Cognition and level of functioning were measured before and after intervention with the Cognitive Abilities Screening Instrument (CASI) and the Lawton Instrumental Activities of Daily Living (IADL). Adherence was assessed by determining dietary intake with a study-specific food frequency questionnaire (FFQ) and red blood cell (RBC) PUFA biomarkers before and after the intervention. Data were analysed by non-parametric analysis of covariance (ANCOVA) with, and without, bootstrap imputation. Results Fifty seven (74% female, mean age: 72 ±7 years) elderly participants participated in this study. There was a significant post intervention difference (P=0.036) in the total CASI scores between the intervention and control groups, when the model was fitted with imputation and controlled for baseline scores. The predicted total CASI score of the intervention group was higher than the score of the control group. Likewise the calculated dietary Omega 3 PUFA intake and red blood cell (RBC) Eicosapentaenoic acid (EPA) and Docosapentaenoic acid (DPA) content differed significantly between the intervention and control group after the intervention phase. The Lawton IADL presented similar results over the course of the study with limited variance. Conclusion Fish intake in the context of the MIND diet may exert a positive effect on cognition as the current study showed that fish can have a significant effect on the cognition of resource-limited elderly after 12 weeks of supplementation of an enhanced diet. Human Nutrition PhD (Dietetics) Unrestricted 2021-11-02T10:19:35Z 2021-11-02T10:19:35Z 2021 2020 Thesis * A2021 http://hdl.handle.net/2263/82473 © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle UCTD
Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial
title Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial
title_full Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial
title_fullStr Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial
title_full_unstemmed Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial
title_short Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled trial
title_sort effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village a randomised controlled trial
topic UCTD
url http://hdl.handle.net/2263/82473