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Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis
Dissertation (MSc (Medical Immunology))--University of Pretoria, 2022.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2022
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| _version_ | 1867613517417283584 |
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| access_status_str | Open Access |
| author2 | Pepper, Michael Sean |
| author_browse | Pepper, Michael Sean |
| author_facet | Pepper, Michael Sean |
| collection | Thesis |
| dc_rights_str_mv | © 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc (Medical Immunology))--University of Pretoria, 2022. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/86431 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:37:24.530Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/86431 Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis Pepper, Michael Sean rachel26364@gmail.com Durandt, Chrisna Ambele, Melvin Giles, Rachel Immunology Assays Adipogenesis Drug targeting 96 well plate UCTD SDG-03: Good health and well-being Dissertation (MSc (Medical Immunology))--University of Pretoria, 2022. The aim of this project was to develop assays that will allow for high-throughput screening to monitor adipogenesis. Such an assay may be useful for the identification of potential drug targets during the process of adipogenesis, which may result in discovering novel solutions to combat obesity and its related comorbidities. The main question for this study is whether adipogenesis can be assessed in smaller well sizes (such as the 96-well plate) with confidence using the specified methods. NRF Masters Scholarship 2020 em2026 Immunology MSc (Medical Immunology) Unrestricted SDG-03: Good health and well-being 2022-07-25T10:44:43Z 2022-07-25T10:44:43Z 2022 2022 Dissertation * S2022 https://repository.up.ac.za/handle/2263/86431 DOI: 10.25403/UPresearchdata.20348028 https://doi.org/10.25403/UPresearchdata.20348028 en © 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | Immunology Assays Adipogenesis Drug targeting 96 well plate UCTD SDG-03: Good health and well-being Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| title | Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| title_full | Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| title_fullStr | Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| title_full_unstemmed | Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| title_short | Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| title_sort | development of a high throughput screening assay to evaluate compound libraries for the modulation of adipogenesis |
| topic | Immunology Assays Adipogenesis Drug targeting 96 well plate UCTD SDG-03: Good health and well-being |
| url | https://repository.up.ac.za/handle/2263/86431 https://doi.org/10.25403/UPresearchdata.20348028 |