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Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa
Thesis (PhD (Medical Microbiology))--University of Pretoria, 2022.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2022
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| _version_ | 1867613486092124160 |
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| access_status_str | Open Access |
| author2 | Ehlers, M.M. (Marthie Magdaleen) |
| author_browse | Ehlers, M.M. (Marthie Magdaleen) |
| author_facet | Ehlers, M.M. (Marthie Magdaleen) |
| collection | Thesis |
| dc_rights_str_mv | © 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Thesis (PhD (Medical Microbiology))--University of Pretoria, 2022. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/86643 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:54.588Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/86643 Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa Ehlers, M.M. (Marthie Magdaleen) rashmikanaidoo@gmail.com Goga, Ameena Ebrahim Naidoo, Rashmika Bronchiectasis Heterogeneous disease Pathogenesis Lung microbiome Resistome Virome HIV virus South Africa UCTD SDG-03: Good health and well-being Thesis (PhD (Medical Microbiology))--University of Pretoria, 2022. Bronchiectasis is a heterogeneous disease with multiple aetiologies and diverse clinical phenotypes. The pathogenesis of bronchiectasis, a growing economic health burden, is poorly understood. While culture-independent technologies have significantly increased the understanding of the lung microbiome, there is limited data on the lung microbiome, resistome and virome from bronchiectasis patients with and without HIV on the African continent. Therefore, the purpose of this study was to identify the lung microbiome, resistome and virome in bronchiectasis patients in Pretoria, South Africa, in order to determine whether HIV status affects the bacterial and viral lung composition and accompanying antimicrobial resistance (AMR) observed. National Research Foundation University of Pretoria em2026 Medical Microbiology PhD (Medical Microbiology) Unrestricted SDG-03: Good health and well-being 2022-08-02T09:14:34Z 2022-08-02T09:14:34Z 2022-09-09 2022 Thesis * S2022 https://repository.up.ac.za/handle/2263/86643 https://doi.org/10.25403/UPresearchdata.20411547 en © 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | Bronchiectasis Heterogeneous disease Pathogenesis Lung microbiome Resistome Virome HIV virus South Africa UCTD SDG-03: Good health and well-being Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa |
| title | Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa |
| title_full | Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa |
| title_fullStr | Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa |
| title_full_unstemmed | Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa |
| title_short | Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa |
| title_sort | lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in pretoria south africa |
| topic | Bronchiectasis Heterogeneous disease Pathogenesis Lung microbiome Resistome Virome HIV virus South Africa UCTD SDG-03: Good health and well-being |
| url | https://repository.up.ac.za/handle/2263/86643 https://doi.org/10.25403/UPresearchdata.20411547 |