Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Characterising some mechanisms of iron homeostasis in selected Armillaria species
Thesis (PhD)--University of Pretoria, 2023.
Saved in:
| Other Authors: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
University of Pretoria
2023
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613521543430144 |
|---|---|
| access_status_str | Open Access |
| author2 | Coetzee, Martin Petrus Albertus |
| author_browse | Coetzee, Martin Petrus Albertus |
| author_facet | Coetzee, Martin Petrus Albertus |
| collection | Thesis |
| dc_rights_str_mv | © 2023 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Thesis (PhD)--University of Pretoria, 2023. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/91580 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:37:28.126Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/91580 Characterising some mechanisms of iron homeostasis in selected Armillaria species Coetzee, Martin Petrus Albertus deborah.narhmensah@up.ac.za Wingfield, Brenda D. Narh Mensah, Deborah Louisa UCTD Genomics Proteomics Bioinformatics Secondary metabolite gene clusters Siderophores Thesis (PhD)--University of Pretoria, 2023. Plant-pathogenic organisms including fungi pose significant risks to agriculture, horticulture, and natural and plantation forests. This affects attainment of some of the 17 Sustainable Development Goals (SDGs) to transform our world. The affected goals include Goal 2 – “End hunger, achieve food security and improved nutrition and promote sustainable agriculture” and Goal 15 – “Protect, restore, and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss”. Species of Armillaria belong to the Physalacriaceae and have a worldwide distribution with a range of plant-pathogenic lifestyles. Current control strategies are inefficient. Hence, there is an urgent need to develop more efficient and sustainable control strategies against the plant-pathogenic members of this group. To achieve this, a deeper understanding is needed about the cellular and molecular defence strategies employed by these fungi. Therefore, the overall objective of this thesis was to increase our understanding of mechanisms employed by Armillaria in comparison to other species in the Physalacriaceae with regards to iron homeostasis. This was done by studying some secondary metabolite gene clusters, and investigating growth, siderophore production, and proteomic and secretomic response of Armillaria species to iron. A multidisciplinary approach including genetics, comparative genomics, in vitro bioassays, and proteomics was employed. The findings of this thesis represent the first study of some mechanisms underpinning iron homeostasis by Armillaria species in comparison to some other members of the Physalacriaceae. Tree Protection Co-operative Programme (TPCP) DSI – NRF South African Research Chairs Initiative (SARChI) in Fungal Genomics (Grant number: 98353) National Research Foundation University of Pretoria Postgraduate Bursary for Masters and Doctoral students Forestry and Agricultural Biotechnology Institute (FABI) PhD Unrestricted 2023-07-21T13:19:33Z 2023-07-21T13:19:33Z 2023-09 2023 Thesis * S2023 http://hdl.handle.net/2263/91580 en © 2023 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Genomics Proteomics Bioinformatics Secondary metabolite gene clusters Siderophores Characterising some mechanisms of iron homeostasis in selected Armillaria species |
| title | Characterising some mechanisms of iron homeostasis in selected Armillaria species |
| title_full | Characterising some mechanisms of iron homeostasis in selected Armillaria species |
| title_fullStr | Characterising some mechanisms of iron homeostasis in selected Armillaria species |
| title_full_unstemmed | Characterising some mechanisms of iron homeostasis in selected Armillaria species |
| title_short | Characterising some mechanisms of iron homeostasis in selected Armillaria species |
| title_sort | characterising some mechanisms of iron homeostasis in selected armillaria species |
| topic | UCTD Genomics Proteomics Bioinformatics Secondary metabolite gene clusters Siderophores |
| url | http://hdl.handle.net/2263/91580 |