Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Echocardiographic evaluation of horses challenged with African horse sickness virus
Mini Dissertation (MMedVet (Diagnostic Imaging))--University of Pretoria, 2023.
Saved in:
| Other Authors: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
University of Pretoria
2024
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613439931711488 |
|---|---|
| access_status_str | Open Access |
| author2 | Carstens, Ann |
| author_browse | Carstens, Ann |
| author_facet | Carstens, Ann |
| collection | Thesis |
| dc_rights_str_mv | © 2023 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Mini Dissertation (MMedVet (Diagnostic Imaging))--University of Pretoria, 2023. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/94462 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:10.076Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/94462 Echocardiographic evaluation of horses challenged with African horse sickness virus Carstens, Ann nicolene.hoepner@up.ac.za Eberhardt, Christina Hoepner, Sara Nicolene UCTD African horse sickness Echocardiography eFoCUS Myocardial Cardiac Mini Dissertation (MMedVet (Diagnostic Imaging))--University of Pretoria, 2023. African horse sickness (AHS) is an infectious, often fatal viral disease of equids with a severe impact on the equine industry in sub-Saharan Africa. Clinicopathological mechanisms are poorly understood, and there is limited information on the degree and type of cardiac involvement. This study followed four horses experimentally infected with African horse sickness virus (AHSV) as part of a vaccine trial to describe echocardiographic changes during the course of the disease. Echocardiography was performed once prior to infection, and daily from infection to humane euthanasia of each subject. Both objective and subjective (eFoCUS) evaluations of all appropriate echocardiographic variables were performed. An increase in diastolic myocardial thickness and a decrease in the size of the left cardiac chambers during diastole and systole were consistent findings on the last day of evaluation of each subject and suggestive of hypovolaemia. The cause of the suspected hypovolaemia was not investigated, but increased vascular permeability causing third space volume loss was considered the most likely cause, as this is associated with the disease process. During the eFoCUS evaluation substantial and perfect interobserver agreement were found for an increase in myocardial thickness and diminution of the left ventricle, respectively, suggesting that these variables could be used to subjectively evaluate intravascular volume in clinical cases in an emergency setting. In addition, perfect interobserver agreement for impaired diastolic dysfunction, and almost perfect agreement for pericardial effusion, was found during the eFoCUS evaluation of the final data sets for each subject. Further studies are needed to objectively define the presence, quantify the severity, identify the cause and significance of these findings. Companion Animal Clinical Studies MMedVet (Diagnostic Imaging) Unrestricted Faculty of Veterinary Science 2024-02-12T08:23:02Z 2024-02-12T08:23:02Z 2024-04 2023 Mini Dissertation * A2024 http://hdl.handle.net/2263/94462 10.25403/UPresearchdata.25124348 en © 2023 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD African horse sickness Echocardiography eFoCUS Myocardial Cardiac Echocardiographic evaluation of horses challenged with African horse sickness virus |
| title | Echocardiographic evaluation of horses challenged with African horse sickness virus |
| title_full | Echocardiographic evaluation of horses challenged with African horse sickness virus |
| title_fullStr | Echocardiographic evaluation of horses challenged with African horse sickness virus |
| title_full_unstemmed | Echocardiographic evaluation of horses challenged with African horse sickness virus |
| title_short | Echocardiographic evaluation of horses challenged with African horse sickness virus |
| title_sort | echocardiographic evaluation of horses challenged with african horse sickness virus |
| topic | UCTD African horse sickness Echocardiography eFoCUS Myocardial Cardiac |
| url | http://hdl.handle.net/2263/94462 |