Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus)
Dissertation (MSc (Veterinary Science))--University of Pretoria, 2021.
Saved in:
| Other Authors: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
University of Pretoria
2024
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613472121946112 |
|---|---|
| access_status_str | Open Access |
| author2 | Buck, Roxanne Kate |
| author_browse | Buck, Roxanne Kate |
| author_facet | Buck, Roxanne Kate |
| collection | Thesis |
| dc_rights_str_mv | © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc (Veterinary Science))--University of Pretoria, 2021. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/95606 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:41.285Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/95606 Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) Buck, Roxanne Kate joel@wildscapesvet.com Tordiffe, Adrian Stephen Wolferstan Alves, Joel Mnandi UCTD Leorpard Zoletil Captive BAM Immobilisation Dissertation (MSc (Veterinary Science))--University of Pretoria, 2021. Objective To compare the immobilisation time and cardiopulmonary effects of zolazepam-tiletamine-medetomidine (ZM) and butorphanol-azaperone-medetomidine (BAM) in captive leopards (Panthera pardus). Study design Prospective, clinical study Materials and Methods 17 adult, captive leopards were immobilised by remote injection of either a combination of zolazepam-tiletamine (1.5 mg kg-1) and medetomidine (0.04 mg kg-1) (ZM, n = 10) or a combination of butorphanol (0.3 mg kg-1), azaperone (0.12 mg kg-1) and medetomidine (0.12 mg kg-1) (BAM, n = 7). Time to safe approach, judged by absent responses to an ear flick and tail tug, was recorded as the immobilisation time. Following immobilisation, cardiopulmonary parameters were recorded and two arterial blood gas samples analysed. After 40 minutes, anaesthesia was reversed using atipamezole (0.2 mg kg-1) for group ZM or atipamezole (0.6 mg kg-1) and naltrexone (0.3 mg kg-1) for group BAM. Recovery time was recorded as time from injection of reversal agent to head up. Data is reported as mean ± standard deviation and compared using a general linear mixed model (p < 0.05). Results For ZM, doses administered were zolazepam-tiletamine 1.3 ± 0.6 mg kg-1 and medetomidine 0.04 ± 0.018 mg kg-1 while those for BAM were butorphanol 0.33 ± 0.05 mg kg-1, azaperone 0.13 ± 0.02 mg kg-1 and medetomidine 0.13 ± 0.02 mg kg-1. Immobilisation time was significantly faster for BAM (5.8 ± 1.1 minutes) than for ZM (11.8 ± 3.3 minutes, p = 0.008). Both treatments resulted in hypertension, with mean arterial blood pressure of 154 ± 46 mmHg with ZM and 137 ± 12 mmHg with BAM. BAM resulted in clinically significant hypoxaemia (arterial oxygen tension 52.8 ± 4.4 mmHg), while arterial oxygen tension was higher with ZM (72.6 ± 8.0 mmHg, p = 0.027). Arterial carbon dioxide tension was lower with ZM (26.4 ± 2.9 mmHg) than BAM (44.8 ± 3.9 mmHg, p < 0.001). Recovery time was not different between treatments (p = 0.604). Conclusion Both combinations provided acceptable immobilisation for field use. Supplementation with oxygen is recommended, especially when using BAM. Companion Animal Clinical Studies MSc (Veterinary Science) Unrestricted 2024-04-17T07:57:56Z 2024-04-17T07:57:56Z 2021 2021-05 Dissertation * S2021 http://hdl.handle.net/2263/95606 en © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Leorpard Zoletil Captive BAM Immobilisation Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) |
| title | Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) |
| title_full | Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) |
| title_fullStr | Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) |
| title_full_unstemmed | Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) |
| title_short | Zolazepam-tiletamine-medetomidine versus butorphanol-azaperone-medetomidine for the immobilisation of captive leopards (Panthera pardus) |
| title_sort | zolazepam tiletamine medetomidine versus butorphanol azaperone medetomidine for the immobilisation of captive leopards panthera pardus |
| topic | UCTD Leorpard Zoletil Captive BAM Immobilisation |
| url | http://hdl.handle.net/2263/95606 |