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Developmental outcomes of HIV-exposed infants in a low-income South African context

Dissertation (MA (Speech-Language Pathology))--University of Pretoria, 2019.

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Other Authors: Kruger, Esedra
Format: Thesis
Language:English
Published: University of Pretoria 2024
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access_status_str Open Access
author2 Kruger, Esedra
author_browse Kruger, Esedra
author_facet Kruger, Esedra
collection Thesis
dc_rights_str_mv © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Dissertation (MA (Speech-Language Pathology))--University of Pretoria, 2019.
format Thesis
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institution University of Pretoria (South Africa)
language English
last_indexed 2026-06-10T12:40:22.637Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher University of Pretoria
publisherStr University of Pretoria
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spelling oai:repository.up.ac.za:2263/97503 Developmental outcomes of HIV-exposed infants in a low-income South African context Kruger, Esedra carmen.vaneck@gmail.com Van der Linde, Jeannie De Beer (nèe van Eck), Carmen Cornelia UCTD HIV-exposed infants Antiretroviral exposure HIV-unexposed infants Developmental outcomes Daily living skills development Socialisation development Dissertation (MA (Speech-Language Pathology))--University of Pretoria, 2019. Background: Effective Human Immunodeficiency Virus (HIV) transmission prevention strategies have led to a growing population of vulnerable HIV-exposed (HE) infants in sub-Saharan Africa, however uncertainty exists in literature regarding their developmental outcomes. Objective: The aim was to determine the developmental outcomes of six- to 12-month-old HE infants in a low-income South African context, when compared to HIV-unexposed (HU) counterparts. Method: In this prospective cross-sectional, group comparison study, the development of 41 HE and 40 HU infants (mean age = 8.4 months, SD = 2.1 months) from a low-income context was assessed. Caregivers were interviewed using a background interview and the Vineland Adaptive Behavior Scales, Third Edition (Vineland-3) to evaluate infants’ communication, daily living, socialisation and motor skills. Results: Based on the overall test scores, the majority of HE participants had age-appropriate development (90.2%; n=37). Some HE participants, however, presented with delays in the domains of communication (9.8%; n=4), daily living skills (2.4%; n=1), socialisation (19.5%; n=8) and motor development (7.3%; n=3). HU participants also demonstrated some domain-specific delays, thus delays were present in both groups. No statistically significant differences were found between the development of HE and HU participants. Conclusion: Findings were reassuring and suggested that the development of HE participants were similar to that of HU counterparts. Developmental differences may, however, only emerge with age, therefore large-scale longitudinal research is recommended. It is suggested that the entire sample was vulnerable, highlighting the importance of developmental surveillance and early intervention in low-income contexts, irrespective of HIV and antiretroviral exposure. Speech-Language Pathology and Audiology MA (Speech-Language Pathology) Unrestricted Faculty of Humanities 2024-08-07T13:20:06Z 2024-08-07T13:20:06Z 2020-04 2019-11 Dissertation * A2020 http://hdl.handle.net/2263/97503 en © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle UCTD
HIV-exposed infants
Antiretroviral exposure
HIV-unexposed infants
Developmental outcomes
Daily living skills development
Socialisation development
Developmental outcomes of HIV-exposed infants in a low-income South African context
title Developmental outcomes of HIV-exposed infants in a low-income South African context
title_full Developmental outcomes of HIV-exposed infants in a low-income South African context
title_fullStr Developmental outcomes of HIV-exposed infants in a low-income South African context
title_full_unstemmed Developmental outcomes of HIV-exposed infants in a low-income South African context
title_short Developmental outcomes of HIV-exposed infants in a low-income South African context
title_sort developmental outcomes of hiv exposed infants in a low income south african context
topic UCTD
HIV-exposed infants
Antiretroviral exposure
HIV-unexposed infants
Developmental outcomes
Daily living skills development
Socialisation development
url http://hdl.handle.net/2263/97503