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Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa
Dissertation (MMedVet (Equine Medicine))--University of Pretoria, 2024.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2024
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| _version_ | 1867613622583164928 |
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| access_status_str | Open Access |
| author2 | Eberhardt, Christina |
| author_browse | Eberhardt, Christina |
| author_facet | Eberhardt, Christina |
| collection | Thesis |
| dc_rights_str_mv | © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MMedVet (Equine Medicine))--University of Pretoria, 2024. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/98378 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:39:04.809Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/98378 Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa Eberhardt, Christina graeme.piketh@up.ac.za Viljoen, Adrienne Piketh, Graeme UCTD Sustainable Development Goals (SDGs) Clinical pathology Onderstepoort Veterinary Academic Hospital Clinical signs Dissertation (MMedVet (Equine Medicine))--University of Pretoria, 2024. Introduction: Equine encephalosis is a systemic disease of horses caused by equine encephalosis virus. This virus is an Orbivirus that is transmitted by biting midges (Culicoides species). Equine encephalosis is often reported as a subclinical infection with a relatively limited number of clinical cases showing predominantly fever, with minimal morbidity and mortality. Rare instances of neurological disease have also been associated with the virus. Clinical relevance: Information regarding the clinical presentation of equine encephalosis is underrepresented in current scientific literature. This study aims to contribute to a more detailed conceptualization of the significance of the disease and its clinical impact. Method: A retrospective, descriptive, observational study was performed on data obtained from the University of Pretoria’s clinical database for cases identified with equine encephalosis over the period 2013-2023. Data from the history, clinical signs and clinicopathological findings were analysed. The clinical presentation and clinicopathological findings are reported. Results: A total of 28 horses conformed to the study parameters as having clinical infection with equine encephalosis virus. Pyrexia was apparent in 89.2% of these cases. Other clinical findings included tachycardia (64.3%), tachypnoea (46.4%), colic (39.3%), neurological signs (21.4%), peripheral oedema (14.3%), and icterus (10.7%). Evaluation of the clinicopathological findings identified lymphopenia (86.7%), thrombocytopenia (76.0%), leukopenia (48.0%), immature neutrophilia (31.8%), and mature neutropenia (27.3%). Conclusion: Equine encephalosis can result in a wide variety of clinical signs in horses and is associated with changes in haematology variables. These haematological changes suggest a systemic response to the viral infection. Further research into the pathophysiology of equine encephalosis is required to better understand the disease and its clinical relevance. Companion Animal Clinical Studies MMedVet (Equine Medicine) Unrestricted Faculty of Veterinary Science SDG-03: Good health and well-being SDG-04: Quality education 2024-09-27T10:29:07Z 2024-09-27T10:29:07Z 2024-09 2024-06 Dissertation * S2024 http://hdl.handle.net/2263/98378 DOI : https://doi.org/10.25403/UPresearchdata.30529316.v1 10.25403/UPresearchdata.30529316 en © 2021 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Sustainable Development Goals (SDGs) Clinical pathology Onderstepoort Veterinary Academic Hospital Clinical signs Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa |
| title | Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa |
| title_full | Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa |
| title_fullStr | Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa |
| title_full_unstemmed | Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa |
| title_short | Clinical signs and clinical pathology findings in horses with equine encephalosis at the Onderstepoort Veterinary Academic Hospital, South Africa |
| title_sort | clinical signs and clinical pathology findings in horses with equine encephalosis at the onderstepoort veterinary academic hospital south africa |
| topic | UCTD Sustainable Development Goals (SDGs) Clinical pathology Onderstepoort Veterinary Academic Hospital Clinical signs |
| url | http://hdl.handle.net/2263/98378 |