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Structural studies on the toxic principle of Ornithogalum Thyrsoides
Dissertation (MSc (Chemistry))--University of Pretoria, 1966.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2024
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| _version_ | 1867613659747844096 |
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| access_status_str | Open Access |
| author2 | Vleggaar, Robert |
| author_browse | Vleggaar, Robert |
| author_facet | Vleggaar, Robert |
| collection | Thesis |
| dc_rights_str_mv | © 2024 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc (Chemistry))--University of Pretoria, 1966. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/99498 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:39:39.821Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/99498 Structural studies on the toxic principle of Ornithogalum Thyrsoides Vleggaar, Robert Van Rooyen, Petrus H. Van der Westhuizen, Driekus Ornithogalum Thyrsoide UCTD Dissertation (MSc (Chemistry))--University of Pretoria, 1966. The main aim of the investigation as described in the thesis, is the isolation and structure elucidation of the toxic principle(s) of the plant 0rnithogalum thyrsoides. Extracts of fresh 0. thyrsoides material were evaluated in a bioassay using weaned guinea pigs. The fractionation of a toxic extract by chromatographic methods on different adsorbents with a variety of eluants was guided by this bioassay and led to the isolation of a single toxic compound for which the trivial name prasinoside G is suggested. The structure viz. 3P-0-(P-o-glucopyranosyl )- 16P-[2-0- (3,4-dimethoxybenzoyl )-P-o-xylopyranosyl-( 1 --3 )-2-0-acetyl-a-L-arabinopyranosyl]-17 ahydroxy- cholest-5-en-22-one is proposed for prasinoside G on the basis of a detailed analysis of its high-field 1H and 13C n.m.r. spectra and two of its derivatives as well as a single-crystal X-ray crystallographic analysis of a hydrolysis product. Detailed results of these studies are given. Chemistry MSc (Chemistry) 2024-11-27T09:16:01Z 2024-11-27T09:16:01Z 22/01/19 1966 Dissertation http://hdl.handle.net/2263/99498 en © 2024 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | Ornithogalum Thyrsoide UCTD Structural studies on the toxic principle of Ornithogalum Thyrsoides |
| title | Structural studies on the toxic principle of Ornithogalum Thyrsoides |
| title_full | Structural studies on the toxic principle of Ornithogalum Thyrsoides |
| title_fullStr | Structural studies on the toxic principle of Ornithogalum Thyrsoides |
| title_full_unstemmed | Structural studies on the toxic principle of Ornithogalum Thyrsoides |
| title_short | Structural studies on the toxic principle of Ornithogalum Thyrsoides |
| title_sort | structural studies on the toxic principle of ornithogalum thyrsoides |
| topic | Ornithogalum Thyrsoide UCTD |
| url | http://hdl.handle.net/2263/99498 |