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Isolation and structure of the metabolites from diplodia maydis
Dissertation (MSc (Chemistry))--University of Pretoria, 1990.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2024
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| _version_ | 1867613523616464896 |
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| access_status_str | Open Access |
| author2 | Vleggaar, Robert |
| author_browse | Vleggaar, Robert |
| author_facet | Vleggaar, Robert |
| collection | Thesis |
| dc_rights_str_mv | © 2024 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc (Chemistry))--University of Pretoria, 1990. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/99617 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:37:30.383Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/99617 Isolation and structure of the metabolites from diplodia maydis Vleggaar, Robert Modro, T.A. Marais, Stephanus Francois Isolation Structure Metabolites Diplodia maydis UCTD Dissertation (MSc (Chemistry))--University of Pretoria, 1990. Investigation of toxic extracts from cultures of the fungus Diplodia maydis (Berk.) Sacc. [ synonyms D. zeae (Schw.) Lev. and Stenocarpella maydis (Berk.)] led to the isolation of diplodiatoxin, a known metabolite, as well as four new metabolites viz. 3-hydroxydiplodiatoxin stenocarpin, steno-carpin 6-0-(4-0-methyl-orsellinate) and carpellin. The structure elucidation of the new compounds is based on a detailed analysis of their highfield 1H and 13 c nuclear magnetic resonance spectra. The relative configurations were deduced from the magnitude of the proton-proton coupling constants and the results obtained from homonuclear proton-proton nuclear Overhauser effect (n.O.e.) studies. The absolute configuration of stenocarpin 6 - 0- ( 4 - 0-methylorsellina te) was determined by the 'partial resolution' method of Horeau. The biosynthetic pathway leading to d±plodiatoxin was investigated by incorporation studies with 13 c-, 2 H and 18 0-labelled precursors. Chemistry MSc (Chemistry) 2024-11-27T09:16:30Z 2024-11-27T09:16:30Z 22/01/18 1990 Dissertation http://hdl.handle.net/2263/99617 en © 2024 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | Isolation Structure Metabolites Diplodia maydis UCTD Isolation and structure of the metabolites from diplodia maydis |
| title | Isolation and structure of the metabolites from diplodia maydis |
| title_full | Isolation and structure of the metabolites from diplodia maydis |
| title_fullStr | Isolation and structure of the metabolites from diplodia maydis |
| title_full_unstemmed | Isolation and structure of the metabolites from diplodia maydis |
| title_short | Isolation and structure of the metabolites from diplodia maydis |
| title_sort | isolation and structure of the metabolites from diplodia maydis |
| topic | Isolation Structure Metabolites Diplodia maydis UCTD |
| url | http://hdl.handle.net/2263/99617 |