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The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample
Thesis (PhD (Anatomy))--University of Pretoria, 2024.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2024
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| _version_ | 1867613486107852801 |
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| access_status_str | Open Access |
| author2 | Uys, Andre |
| author_browse | Uys, Andre |
| author_facet | Uys, Andre |
| collection | Thesis |
| dc_rights_str_mv | © 2023 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Thesis (PhD (Anatomy))--University of Pretoria, 2024. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/99744 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:54.588Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/99744 The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample Uys, Andre chane.smit@up.ac.za Van Heerden, Willem Francois Petrus Fonseca, Felipe Paiva Smit, Chane UCTD Sustainable Development Goals (SDGs) Ameloblastoma Histopathologic variants Radiologic features Proliferation index Odontogenic Neoplasm Thesis (PhD (Anatomy))--University of Pretoria, 2024. In this thesis, The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample, the candidate aimed to assess factors that influence the behaviour of these odontogenic neoplasms. Our understanding of this neoplasm is paramount due to its high prevalence in South Africa and its burden on the healthcare system. In the study, ameloblastomas were diagnosed at a significantly younger age compared to patients from developed countries. Statistically significant associations between aggressive radiologic features with age and lesion duration were noted, emphasising the importance of timeous treatment to reduce patient morbidity. Faster growth correlated with radiologic signs of aggressiveness was also noted amongst female patients. The indolent behaviour of the unicystic variant was supported by their clinicoradiologic findings and the lowest overall proliferation index. The high proliferation index of the plexiform variant correlated with aggressive clinicoradiologic features, demonstrating more aggressive behaviour. The findings of this study have expanded the current understanding of this neoplasm with improvements in clinical management. Anatomy PhD (Anatomy) Restricted Faculty of Health Sciences SDG-03: Good health and well-being 2024-12-04T07:16:22Z 2024-12-04T07:16:22Z 2025-04 2024-12 Thesis * A2025 http://hdl.handle.net/2263/99744 10.25403/UPresearchdata.27939795 en © 2023 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Sustainable Development Goals (SDGs) Ameloblastoma Histopathologic variants Radiologic features Proliferation index Odontogenic Neoplasm The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample |
| title | The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample |
| title_full | The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample |
| title_fullStr | The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample |
| title_full_unstemmed | The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample |
| title_short | The radiologic features, histopathologic variants and proliferation indices of ameloblastomas in a South African sample |
| title_sort | radiologic features histopathologic variants and proliferation indices of ameloblastomas in a south african sample |
| topic | UCTD Sustainable Development Goals (SDGs) Ameloblastoma Histopathologic variants Radiologic features Proliferation index Odontogenic Neoplasm |
| url | http://hdl.handle.net/2263/99744 |