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Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa

Thesis (MPhil)--Stellenbosch University, 2017

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Main Author: Kapembwa, Kenneth Chali
Other Authors: Davids, M. R.
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2017
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access_status_str Open Access
author Kapembwa, Kenneth Chali
author2 Davids, M. R.
author_browse Davids, M. R.
Kapembwa, Kenneth Chali
author_facet Davids, M. R.
Kapembwa, Kenneth Chali
author_sort Kapembwa, Kenneth Chali
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MPhil)--Stellenbosch University, 2017
format Thesis
id oai:scholar.sun.ac.za:10019.1/102098
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:44:48.111Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2017
publishDateRange 2017
publishDateSort 2017
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/102098 Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa Kapembwa, Kenneth Chali Davids, M. R. Bapoo, N. A. Tannor, E. K. Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Nephrology. Dialyzers (Artificial kidney) Peritoneal dialysis Kidneys -- Diseases Hemodialysis UCTD Thesis (MPhil)--Stellenbosch University, 2017 Background: Peritoneal dialysis (PD) technique failure invariably occurs in patients with end-stage renal disease who are treated with this modality and results in increased morbidity and mortality. Various factors have been associated with the development of technique failure. Identifying such factors in a PD program is important to minimize the rates of technique failure and maintain patients on PD. Methods: In this retrospective study at Tygerberg Hospital in Cape Town, South Africa, we studied 170 patients who were started on CAPD and determined rates of technique and patient survival. Demographic, clinical and laboratory data were assessed to identify risk factors for these outcomes. Results: The median age of the patients was 36 years with the commonest cause of ESRD being glomerulonephritis. Only one patient had diabetes mellitus. Technique survival at 1, 2, 3 and 5 years was 78.5%, 60.4%, 54.5% and 39.6% respectively while patient survival was 90.8%, 86.8%, 83.6% and 63.5%. Peritonitis was the most common cause of technique failure. On multivariate analysis, the occurrence of peritonitis (OR 57.41, CI 11.19- 294.70, p < 0.001) and Black race (OR 6.43, CI 1.58-26.14, p = 0.009) increased the likelihood of technique failure. Other clinical and social factors were not significantly associated with the occurrence of technique failure. Conclusion: In our ESRD patients on PD, Black race and peritonitis were important factors in the development of technique failure. Concerted efforts are required to reduce peritonitis rates at our centre as this is the main cause of technique failure. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar 2017-08-14T10:28:39Z 2017-08-14T10:28:39Z 2017-03 Thesis http://hdl.handle.net/10019.1/102098 en_ZA http://hdl.handle.net/10019.1/102099 Stellenbosch University 24 pages application/pdf application/pdf Stellenbosch : Stellenbosch University
spellingShingle Dialyzers (Artificial kidney)
Peritoneal dialysis
Kidneys -- Diseases
Hemodialysis
UCTD
Kapembwa, Kenneth Chali
Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa
title Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa
title_full Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa
title_fullStr Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa
title_full_unstemmed Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa
title_short Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa
title_sort peritoneal dialysis technique survival at tygerberg hospital in cape town south africa
topic Dialyzers (Artificial kidney)
Peritoneal dialysis
Kidneys -- Diseases
Hemodialysis
UCTD
url http://hdl.handle.net/10019.1/102098
work_keys_str_mv AT kapembwakennethchali peritonealdialysistechniquesurvivalattygerberghospitalincapetownsouthafrica