Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland.
Thesis (MFamMed)--Stellenbosch University, 2018.
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | en_ZA |
| Published: |
Stellenbosch : Stellenbosch University
2018
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613739424940032 |
|---|---|
| access_status_str | Open Access |
| author | Ndakit, Manighuli Kambasu |
| author2 | Blitz, Julia |
| author_browse | Blitz, Julia Ndakit, Manighuli Kambasu |
| author_facet | Blitz, Julia Ndakit, Manighuli Kambasu |
| author_sort | Ndakit, Manighuli Kambasu |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (MFamMed)--Stellenbosch University, 2018. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/103664 |
| institution | Stellenbosch University (South Africa) |
| language | en_ZA |
| last_indexed | 2026-06-10T12:40:56.191Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/103664 Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. Ndakit, Manighuli Kambasu Blitz, Julia Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Family and Emergency Medicine. Family Medicine and Primary Care. Highly active antiretroviral therapy -- Swaziland HIV-positive women -- Nhlangano (Swaziland) HIV (Viruses) -- Transmission Médecins sans frontières (Association). -- Swaziland Nhlangano Health Centre -- Nhlangano (Swaziland) UCTD Thesis (MFamMed)--Stellenbosch University, 2018. ENGLISH SUMMARY : Epidemic of HIV infection is hitting Swaziland where the prevalence is among the highest in the world. Nhlangano Health Centre (NHC) in collaboration with Medecins Sans Frontiers Switzerland (MSF Switzerland) opted to hit early by starting Highly Active Anti-retroviral Therapy (HAART) among HIV infected pregnant women with CD4 count cells above 350. This new intervention raised concerns on acceptability and adherence which needed to be assessed. Study design: This was a descriptive study which explored the acceptance of and adherence of pregnant women to full anti-retroviral therapy at Nhlangano Health Centre in the period from 24th June 2014 to 23rd June 2015. The level of adherence was assessed by announced pill counts on subsequent visits. Then, 6 months after initiation, the viral load and a second CD4 count were determined. Results: 98 participants were recruited and initiated; one later died. 80.6% resided in the rural area. 80.6% attended secondary school. Majority were single (79.6%). Mean age was 25.4 years. 64.3% booked at 2nd trimester. Most were multiparous (75.5%). Mean haemoglobin was 11.1g/dl. After 6 months, mean CD4 count was 709.4 up from 554.4 (initial) and 66 (95.6%) had undetectable viral load risen from 14 (20.2%) at initiation. 69 participants (70.4%) were adherent to treatment; 3 (3.1%) of them failed to suppress completely the viral loads. 13 pregnant women refused HAART; of these 12 were interviewed and one declined. The rate of acceptance was 88.3%. Conclusion: Most of the HIV infected pregnant women who visited the clinic accepted the treatment, their CD4 count increased and had undetectable viral loads after 6 months. Anti-retroviral therapy is effective and can be successfully initiated in pregnant women with CD4 count above 350 but should be monitored closely to avoid loss to follow-up. AFRIKAANSE OPSOMMING : Geen opsomming beskikbaar. 2018-03-02T09:41:26Z 2018-04-09T07:05:34Z 2018-03-02T09:41:26Z 2018-04-09T07:05:34Z 2018-03 Thesis http://hdl.handle.net/10019.1/103664 en_ZA Stellenbosch University 39, pages ; illustrations, includes annexure application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Highly active antiretroviral therapy -- Swaziland HIV-positive women -- Nhlangano (Swaziland) HIV (Viruses) -- Transmission Médecins sans frontières (Association). -- Swaziland Nhlangano Health Centre -- Nhlangano (Swaziland) UCTD Ndakit, Manighuli Kambasu Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. |
| title | Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. |
| title_full | Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. |
| title_fullStr | Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. |
| title_full_unstemmed | Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. |
| title_short | Acceptance of and adherence to full anti-retroviral therapy for prevention of mother to child transmission in HIV infected pregnant women with CD4 count above 350 at Nhlangano Health Centre, Swaziland. |
| title_sort | acceptance of and adherence to full anti retroviral therapy for prevention of mother to child transmission in hiv infected pregnant women with cd4 count above 350 at nhlangano health centre swaziland |
| topic | Highly active antiretroviral therapy -- Swaziland HIV-positive women -- Nhlangano (Swaziland) HIV (Viruses) -- Transmission Médecins sans frontières (Association). -- Swaziland Nhlangano Health Centre -- Nhlangano (Swaziland) UCTD |
| url | http://hdl.handle.net/10019.1/103664 |
| work_keys_str_mv | AT ndakitmanighulikambasu acceptanceofandadherencetofullantiretroviraltherapyforpreventionofmothertochildtransmissioninhivinfectedpregnantwomenwithcd4countabove350atnhlanganohealthcentreswaziland |