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Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa

Thesis (MFamMed)--Stellenbosch University, 2022.

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Main Author: Williams, Andrew
Other Authors: Pather, Michael Karl
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2020
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access_status_str Open Access
author Williams, Andrew
author2 Pather, Michael Karl
author_browse Pather, Michael Karl
Williams, Andrew
author_facet Pather, Michael Karl
Williams, Andrew
author_sort Williams, Andrew
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MFamMed)--Stellenbosch University, 2022.
format Thesis
id oai:scholar.sun.ac.za:10019.1/109058
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:41:10.692Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
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source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/109058 Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa Williams, Andrew Pather, Michael Karl Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Family and Emergency Medicine. Family Medicine and Primary Care. Tuberculosis in children -- Diagnosis -- South Africa Tuberculosis -- Diagnosis -- South Africa Pulmonary Tuberculosis UCTD Thesis (MFamMed)--Stellenbosch University, 2022. ENGLISH SUMMARY: Background: TB remains one of the top 10 leading causes of death worldwide as millions of people still contract the disease annually. It is estimated that TB caused between 1.2 and 1.4 million deaths globally in 2017. The incidence of TB in children is a reflection of the underlying factors that fuel the TB epidemic, as these infections reflect ongoing TB-transmission. Aim: To describe how the diagnosis of Pulmonary Tuberculosis (PTB) in children under 5 years is made in the Langeberg sub-district. Setting: The Langeberg sub-district includes Robertson and Montagu District Hospitals as well as their surrounding clinics. A total of nine primary healthcare (PHC) clinics as well as two mobile clinics serving the farm areas in the sub-district were included. Methods: A retrospective descriptive study was conducted. The researcher obtained statistics from the information management department of the Langeberg sub-district and utilised information of all known and notified cases of tuberculosis in the district. All cases of PTB diagnosed from 1st January 2018 to 31st December 2018, in children under 5 years of age were included. Results: A total sample of 166 folders were reviewed. A proven positive adult contact was identified in 39% of cases. A suggestive chest x-ray was found in 93,4% of cases although specific CXR findings were not documented. Gastric washings were done in 52 of the children and had a positive yield of 13%. A total of 4,7% had HIV/TB co-infection and 12% had comorbid malnutrition. 85,5% of children had a positive treatment outcome (treatment completed or cured). Conclusion: The diagnosis of PTB in children primarily remains a radiological diagnosis, but clinical factors like symptoms and their duration, weight trends and the presence of an adult contact have also been considered. Microbiological confirmation was absent in the majority of cases started on TB treatment. Comorbid HIV infection, malnutrition or asthma did not contribute to increased risk for adverse outcomes. Contact tracing needs to be improved within the sub-district. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2020-11-24T12:55:50Z 2021-01-31T18:20:37Z 2020-11-24T12:55:50Z 2021-01-31T18:20:37Z 2020-12 Thesis http://hdl.handle.net/10019.1/109058 en_ZA Stellenbosch University 15 pages : illustrations application/pdf Stellenbosch : Stellenbosch University
spellingShingle Tuberculosis in children -- Diagnosis -- South Africa
Tuberculosis -- Diagnosis -- South Africa
Pulmonary Tuberculosis
UCTD
Williams, Andrew
Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
title Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
title_full Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
title_fullStr Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
title_full_unstemmed Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
title_short Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
title_sort assessment diagnosis and management of pulmonary tuberculosis in children under five years of age in the langeberg sub district western cape south africa
topic Tuberculosis in children -- Diagnosis -- South Africa
Tuberculosis -- Diagnosis -- South Africa
Pulmonary Tuberculosis
UCTD
url http://hdl.handle.net/10019.1/109058
work_keys_str_mv AT williamsandrew assessmentdiagnosisandmanagementofpulmonarytuberculosisinchildrenunderfiveyearsofageinthelangebergsubdistrictwesterncapesouthafrica