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The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town

Thesis (MFamMed)--Stellenbosch University, 2020.

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Main Author: Swarts, Lynne
Other Authors: Van Hoving, Daniel J.
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2020
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access_status_str Open Access
author Swarts, Lynne
author2 Van Hoving, Daniel J.
author_browse Swarts, Lynne
Van Hoving, Daniel J.
author_facet Van Hoving, Daniel J.
Swarts, Lynne
author_sort Swarts, Lynne
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MFamMed)--Stellenbosch University, 2020.
format Thesis
id oai:scholar.sun.ac.za:10019.1/109080
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:43:58.501Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/109080 The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town Swarts, Lynne Van Hoving, Daniel J. Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Family and Emergency Medicine. Emergency Medicine. HIV-positive persons -- Mortality -- Khayelitsha (Cape Town, South Africa) Tuberculosis -- Patients -- Mortality -- Khayelitsha (Cape Town, South Africa) Trauma centers -- Khayelitsha (Cape Town, South Africa) Resuscitation UCTD Thesis (MFamMed)--Stellenbosch University, 2020. ENGLISH SUMMARY : Introduction: Many patients present to emergency centres with HIV and tuberculosis related emergencies. Little is known about the influence of HIV and tuberculosis on the resuscitation areas of district-level hospitals. The primary objective was to determine the prevalence and in-hospital mortality of patients with HIV and/or tuberculosis presenting to the resuscitation area of Khayelitsha Hospital, Cape Town. Methods: A retrospective analysis was performed on a prospectively collected observational database. A randomly selected 12-week sample of data was used. Trauma and paediatric (< 13 years) cases were excluded. Patient demographics, HIV and tuberculosis status, disease presentation, investigations and procedures undertaken, disposition and in-hospital mortality were assessed. HIV and tuberculosis status were determined by laboratory confirmation or from clinical records. Descriptive statistics are presented and comparisons for categorical data were done using the χ2-test. Results: A total of 370 patients were included. HIV prevalence was 38.4% (n=142; unknown status n=78, 21.1%) and tuberculosis prevalence 13.5% (n=50; unknown status n=233, 63%). The HIV/tuberculosis coinfection rate was 10.8%. Age (mean 42.5 years) and gender distribution (male 40.3%) were similar amongst HIV and tuberculosis groups. Intentional overdose presentations were more frequent in the HIV positive group (14.8% vs 8.7%, p<0.01). HIV-negative patients were less likely to receive an abdominal ultrasound examination (p<0.01) to aid in excluding extra-pulmonary tuberculosis and received less intravenous antibiotics (p<0.01). In-hospital mortality was 17% and was not influenced by HIV status (p=0.27) or tuberculosis status (p=0.27). Conclusion: This study highlights the influence of both HIV and tuberculosis on the resuscitation area of a district level hospital. Neither HIV nor tuberculosis status were associated with in-hospital mortality. The high prevalence of intentional overdose may reflect underlying social concerns that need to be addressed. AFRIKAANSE OPSOMMING : Geen opsomming beskikbaar. Masters 2020-06-30T10:09:50Z 2021-01-31T19:34:31Z 2020-06-30T10:09:50Z 2021-01-31T19:34:31Z 2020-12 Thesis http://hdl.handle.net/10019.1/109080 en_ZA Stellenbosch University 53 pages ; illustrations application/pdf Stellenbosch : Stellenbosch University
spellingShingle HIV-positive persons -- Mortality -- Khayelitsha (Cape Town, South Africa)
Tuberculosis -- Patients -- Mortality -- Khayelitsha (Cape Town, South Africa)
Trauma centers -- Khayelitsha (Cape Town, South Africa)
Resuscitation
UCTD
Swarts, Lynne
The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town
title The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town
title_full The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town
title_fullStr The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town
title_full_unstemmed The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town
title_short The prevalence and in-hospital mortality of patients with HIV and tuberculosis admitted to resuscitation area of an urban district-level hospital in Cape Town
title_sort prevalence and in hospital mortality of patients with hiv and tuberculosis admitted to resuscitation area of an urban district level hospital in cape town
topic HIV-positive persons -- Mortality -- Khayelitsha (Cape Town, South Africa)
Tuberculosis -- Patients -- Mortality -- Khayelitsha (Cape Town, South Africa)
Trauma centers -- Khayelitsha (Cape Town, South Africa)
Resuscitation
UCTD
url http://hdl.handle.net/10019.1/109080
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AT swartslynne prevalenceandinhospitalmortalityofpatientswithhivandtuberculosisadmittedtoresuscitationareaofanurbandistrictlevelhospitalincapetown