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Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life

Thesis (MMed)--Stellenbosch University, 2022.

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Bibliographic Details
Main Author: Ebrahim, Mohamedraza
Other Authors: Kali, Gugulabatembunamahlubi
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2020
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access_status_str Open Access
author Ebrahim, Mohamedraza
author2 Kali, Gugulabatembunamahlubi
author_browse Ebrahim, Mohamedraza
Kali, Gugulabatembunamahlubi
author_facet Kali, Gugulabatembunamahlubi
Ebrahim, Mohamedraza
author_sort Ebrahim, Mohamedraza
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MMed)--Stellenbosch University, 2022.
format Thesis
id oai:scholar.sun.ac.za:10019.1/109448
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:44:10.803Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/109448 Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life Ebrahim, Mohamedraza Kali, Gugulabatembunamahlubi Fourie, Barend Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Paediatrics and Child Health. Methamphetamine Newborn screening Antenatal exposure Effects of drugs UCTD Thesis (MMed)--Stellenbosch University, 2022. ENGLISH ABSTRACT: Methamphetamine use is a significant problem in the Western Cape province. Antenatal exposure of the foetus to methamphetamine has been reported to have deleterious effects, including effects on the cardiovascular system. In this case series, we report on thirteen infants who had been exposed to methamphetamine in utero, with last documented use ranging from 2 days to a month before delivery. The infants were either born at Tygerberg Hospital (TBH), or had been outborn and referred to TBH within 72 hours of birth. They all had methamphetamine screens in the urine and echocardiographic studies, and 9 neonates had 24-hour Holter electrocardiogram monitoring. Four (30.8%) of the neonates tested positive for methamphetamine. Five (38.5%) infants had acyanotic cardiac lesions diagnosed, and 2 (15.4%) had abnormal heart rhythm patterns. 3/5 (60%) of the cardiac lesions were most likely related to prematurity. Further large prospective studies are needed to clearly delineate the effects of methamphetamine exposure on the cardiovascular system in neonates. "Geen opsomming biskikbaar" Masters 2020-11-16T12:32:56Z 2021-02-01T07:55:36Z 2020-11-16T12:32:56Z 2021-02-01T07:55:36Z 2020-12 Thesis http://hdl.handle.net/10019.1/109448 en_ZA Stellenbosch University ix, 56 pages application/pdf Stellenbosch : Stellenbosch University
spellingShingle Methamphetamine
Newborn screening
Antenatal exposure
Effects of drugs
UCTD
Ebrahim, Mohamedraza
Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life
title Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life
title_full Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life
title_fullStr Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life
title_full_unstemmed Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life
title_short Case series on methamphetamine exposure in pregnancy : heart rhythm patterns of newborns in the first week of life
title_sort case series on methamphetamine exposure in pregnancy heart rhythm patterns of newborns in the first week of life
topic Methamphetamine
Newborn screening
Antenatal exposure
Effects of drugs
UCTD
url http://hdl.handle.net/10019.1/109448
work_keys_str_mv AT ebrahimmohamedraza caseseriesonmethamphetamineexposureinpregnancyheartrhythmpatternsofnewbornsinthefirstweekoflife