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Pulmonary Echinococcus in children: a descriptive study in a LMIC
Thesis (MMed)--Stellenbosch University, 2021.
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| Other Authors: | |
| Format: | Thesis |
| Language: | en_ZA |
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Stellenbosch : Stellenbosch University
2021
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| _version_ | 1867613776713351168 |
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| access_status_str | Open Access |
| author | Mfingwana, Lunga |
| author2 | Goussard, Pierre |
| author_browse | Goussard, Pierre Mfingwana, Lunga |
| author_facet | Goussard, Pierre Mfingwana, Lunga |
| author_sort | Mfingwana, Lunga |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (MMed)--Stellenbosch University, 2021. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/123828 |
| institution | Stellenbosch University (South Africa) |
| language | en_ZA |
| last_indexed | 2026-06-10T12:41:31.332Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/123828 Pulmonary Echinococcus in children: a descriptive study in a LMIC Mfingwana, Lunga Goussard, Pierre Van Wyk, Lizelle Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Paediatrics and Child Health. Pulmonary Echinococcus Echinococcus granulosus Lower middle income countries (LMIC) UCTD Echinococcus -- Children Hydatid cysts Thesis (MMed)--Stellenbosch University, 2021. Background: Echinococcus granulosus is a major public health problem in lower middle- income countries (LMIC). Children are commonly diagnosed with cysts in the lungs and/or the liver. Objectives: The purpose of this study was to describe a pediatric cohort diagnosed with pulmonary cystic echinococcus (CE) and treated with a combination of medical and surgical therapy. Methods: This was a retrospective study performed between July 2017 and December 2020 at Tygerberg Hospital, South Africa. Clinical, laboratory, radiological, medical, and surgery-related outcomes were reviewed. Results: The cohort consisted of 35 children, 17 (49%) were male, with a mean age of 9 ±5.4 years and a mean weight of 20.3 ±8.3 kg. The most frequently encountered presenting symptom was cough (93%) followed by fever (70% ). Isolated pulmonary CE accounted for the majority of cases (74%) with left lower lobe predominance. A significant proportion of the cohort exhibited chest computed tomography (CT) characteristics consistent with complicated pulmonary CE. Eighteen (58%) children had a positive indirect hemagglutination assay test result. All children received medical treatment whilst 3 0 (86%) of children required surgery. Children with complicated pulmonary CE stayed a mean of 12.5 ±6.6 days, while those with simple cysts stayed 6.8 ±1.5 days. Conclusion: Isolated pulmonary CE is common in children, whereas extrapulmonary cysts are uncommon. Pulmonary CE is diagnosed using CXR, and CT imaging. IHA serology has limited diagnostic utility for pulmonary CE. Combined surgery and chemotherapy remain the gold standard for treating pulmonary CE. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar Masters 2021-11-25T09:03:46Z 2021-12-22T14:23:46Z 2021-11-25T09:03:46Z 2021-12-22T14:23:46Z 2021-12 Thesis http://hdl.handle.net/10019.1/123828 en_ZA Stellenbosch University 27 pages application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Pulmonary Echinococcus Echinococcus granulosus Lower middle income countries (LMIC) UCTD Echinococcus -- Children Hydatid cysts Mfingwana, Lunga Pulmonary Echinococcus in children: a descriptive study in a LMIC |
| title | Pulmonary Echinococcus in children: a descriptive study in a LMIC |
| title_full | Pulmonary Echinococcus in children: a descriptive study in a LMIC |
| title_fullStr | Pulmonary Echinococcus in children: a descriptive study in a LMIC |
| title_full_unstemmed | Pulmonary Echinococcus in children: a descriptive study in a LMIC |
| title_short | Pulmonary Echinococcus in children: a descriptive study in a LMIC |
| title_sort | pulmonary echinococcus in children a descriptive study in a lmic |
| topic | Pulmonary Echinococcus Echinococcus granulosus Lower middle income countries (LMIC) UCTD Echinococcus -- Children Hydatid cysts |
| url | http://hdl.handle.net/10019.1/123828 |
| work_keys_str_mv | AT mfingwanalunga pulmonaryechinococcusinchildrenadescriptivestudyinalmic |