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Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting

Thesis (MMed)--Stellenbosch University, 2021

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Main Author: Kombo, Lena
Other Authors: Smith, Johan
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University, 2021 2021
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access_status_str Open Access
author Kombo, Lena
author2 Smith, Johan
author_browse Kombo, Lena
Smith, Johan
author_facet Smith, Johan
Kombo, Lena
author_sort Kombo, Lena
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MMed)--Stellenbosch University, 2021
format Thesis
id oai:scholar.sun.ac.za:10019.1/124270
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:47:03.084Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher Stellenbosch : Stellenbosch University, 2021
publisherStr Stellenbosch : Stellenbosch University, 2021
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/124270 Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting Kombo, Lena Smith, Johan Van Wyk, Lizelle Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Paediatrics and Child Health. Somatic growth Birth weight, Low Enteral feeding of children Fetus -- Growth UCTD Thesis (MMed)--Stellenbosch University, 2021 ENGLISH ABSTRACT: Aim: To determine the growth and prevalence of extrauterine growth restriction (EUGR) in extremely low birth weight (ELBW) infants receiving enteral-only nutrition in a resource-restricted environment. Methods: In 72 ELBW (<1000g) infants, admitted over a one-year period to Tygerberg Hospital, Cape Town, South Africa, information on nutritional intake, largely from fortified breastmilk was retrospectively collected. Anthropometric data for the first 49 postnatal days was compared to gender-specific INTERGROWTH-21st standards. Results: Full enteral feeds (150 ml/kg) were reached by day 10-14 with energy >100 Kcal/kg/day from day 10, and protein >3.5mg/kg/day from day 14, onwards. Growth velocity remained below 15g/kg/day at day 49. INTERGROWTH-21st Z-scores decreased from -0.8 ± 1.1 at birth to -2.4 ± 1.5 at day 49. Adequate weight growth velocity (≥15g/kg/d) was associated with maternal hypertension, completed antenatal steroids, caesarean section delivery, and small for gestational age status. Conclusion: This is the first study to evaluate growth of ELBW infants in a resource-restricted setting where enteral-only nutrition, principally from fortified breastmilk, was the primary feeding option. The incidence of EUGR, although high, was similar to the incidence in well-resourced settings, where total parenteral nutrition is routinely provided. Key notes: Extra-uterine growth restriction (EUGR) is high in extremely low birth weight infants receiving enteral-only nutrition. However, EUGR rates are similar to infants receiving parenteral nutrition. Despite developmental immaturity it is possible for these infants to achieve fetal growth rates. Enteral-only feeding regimens, especially in restricted-resource environments, should be regularly audited to ensure provision of feeds with optimal protein, and protein to energy ratios. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2021-11-21T16:22:51Z 2022-02-22T10:21:53Z 2021-11-21T16:22:51Z 2021-04 Thesis http://hdl.handle.net/10019.1/124270 en_ZA Stellenbosch University 19 pages : illustrations application/pdf Stellenbosch : Stellenbosch University, 2021
spellingShingle Somatic growth
Birth weight, Low
Enteral feeding of children
Fetus -- Growth
UCTD
Kombo, Lena
Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting
title Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting
title_full Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting
title_fullStr Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting
title_full_unstemmed Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting
title_short Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting
title_sort somatic growth of enteral only fed extremely low birth weight infants in a resource restricted setting
topic Somatic growth
Birth weight, Low
Enteral feeding of children
Fetus -- Growth
UCTD
url http://hdl.handle.net/10019.1/124270
work_keys_str_mv AT kombolena somaticgrowthofenteralonlyfedextremelylowbirthweightinfantsinaresourcerestrictedsetting