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Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.

Thesis (MMed)--Stellenbosch University, 2021

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Main Author: Dormohamed, Nayirat
Other Authors: LLoyd, Lizel
Format: Thesis
Language:en_ZA
Published: 2021
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access_status_str Open Access
author Dormohamed, Nayirat
author2 LLoyd, Lizel
author_browse Dormohamed, Nayirat
LLoyd, Lizel
author_facet LLoyd, Lizel
Dormohamed, Nayirat
author_sort Dormohamed, Nayirat
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MMed)--Stellenbosch University, 2021
format Thesis
id oai:scholar.sun.ac.za:10019.1/124271
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:45:33.890Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2021
publishDateRange 2021
publishDateSort 2021
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source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/124271 Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa. Dormohamed, Nayirat LLoyd, Lizel Van Wyk, Lizelle Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Paediatrics and Child Health. Gestational age -- South Africa Newborn infants -- Mortality -- South Africa Newborn morbidity -- South Africa Neonatology -- South Africa UCTD Thesis (MMed)--Stellenbosch University, 2021 ENGLISH ABSTRACT: Background: Periviability, defined as a gestational age of 20 0/7 to 25 6/7 weeks, is considered the limit of foetal maturity in developed countries, where a reasonable chance of survival exists. The outcome of these neonates in Sub-Saharan Africa is poorly described. Objectives: The study aimed to describe the mortality and morbidities of periviable neonates admitted to a resource-restricted hospital in South Africa. Methods: This was a retrospective, descriptive study performed at Tygerberg Hospital, Cape Town, South Africa, between January 2017 and December 2018. All periviable neonates, defined as a gestational age ≤27 weeks and/or birth weight of ≤750g, born at, or admitted to, Tygerberg Hospital within 24 hours of age, were included. Results: The study population consisted of 186 periviable neonates: 157 (84.4%) of the neonates were ≤27 weeks, 101 (54.3%) were ≤750g and 72 (38.7%) were ≤27 weeks and ≤750g at birth. Sixteen percent of periviable neonates had a birthweight <3rd centile i.e., severe intrauterine growth restriction (IUGR). Neonatal morbidities varied with gestational age. Overall survival rate was 51.1%, with survival increasing with increasing gestational age. Morbidities per gestational age and birth weight category are described. Most periviable neonates received comfort care or specific supportive care only, congruent with the provincial periviability guidelines. Conclusion: This is the first study to describe survival and morbidities of neonates delivered at the periviable limit of gestational age, defined as a gestational age ≤27 weeks and/or birth weight of ≤750g, in a resource-restricted hospital in South Africa. Despite restricted resources and limited care, nearly 50% of periviable neonates survived. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2021-11-21T16:18:04Z 2022-02-22T10:21:56Z 2021-11-21T16:18:04Z 2021-04 Thesis http://hdl.handle.net/10019.1/124271 en_ZA Stellenbosch University 17 pages : illustrations application/pdf
spellingShingle Gestational age -- South Africa
Newborn infants -- Mortality -- South Africa
Newborn morbidity -- South Africa
Neonatology -- South Africa
UCTD
Dormohamed, Nayirat
Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.
title Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.
title_full Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.
title_fullStr Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.
title_full_unstemmed Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.
title_short Outcomes of periviable neonates admitted to a resource-restricted hospital, Cape Town, South Africa.
title_sort outcomes of periviable neonates admitted to a resource restricted hospital cape town south africa
topic Gestational age -- South Africa
Newborn infants -- Mortality -- South Africa
Newborn morbidity -- South Africa
Neonatology -- South Africa
UCTD
url http://hdl.handle.net/10019.1/124271
work_keys_str_mv AT dormohamednayirat outcomesofperiviableneonatesadmittedtoaresourcerestrictedhospitalcapetownsouthafrica