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Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework

Thesis (MMed) -- Stellenbosch University, 2022.

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Main Author: Van der Merwe, Carine
Other Authors: Slogrove, Amy
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2022
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access_status_str Open Access
author Van der Merwe, Carine
author2 Slogrove, Amy
author_browse Slogrove, Amy
Van der Merwe, Carine
author_facet Slogrove, Amy
Van der Merwe, Carine
author_sort Van der Merwe, Carine
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MMed) -- Stellenbosch University, 2022.
format Thesis
id oai:scholar.sun.ac.za:10019.1/126158
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:45:58.010Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/126158 Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework Van der Merwe, Carine Slogrove, Amy Engelbrecht, Arnold Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Paediatrics and Child Health. Birth weight, Low -- Worcester (South Africa) Newborn infants -- Mortality -- Worcester (South Africa) Prematurely born children -- Worcester (South Africa) Neonatology -- Worcester (South Africa) UCTD Thesis (MMed) -- Stellenbosch University, 2022. ENGLISH ABSTRACT: Background: A significant proportion of very-low-birthweight (VLBW; <1500g) infants are born at regional hospitals in South Africa (SA) and little is known regarding their care and outcomes. Since 2017, clinicians at regional hospitals throughout the Western Cape (WC) have utilized the WC Department of Health Periviability Decision Support Framework to guide care of VLBW infants. Objectives: To describe care of VLBW infants at Worcester Provincial Hospital (WPH) in 2018, compared to recommendations in the Framework and to secondarily compare differences in shortterm outcomes of VLBW infants managed before (2016) and after (2018) the implementation of these guidelines. Methods: A retrospective cohort study was conducted of all live-born VLBW infants ≤7 days managed at WPH, in 2016 and 2018. Information related to neonatal care was collected from medical records of patients born in 2018 only, and compared with Framework recommendations according to birthweight categories (500-799g; 800-999g; 1000-1499g). Information regarding mortality at discharge and at age 12 months, readmission before age 12 months, and length of neonatal stay was captured for all included neonates. Results were reported using frequencies, percentages, and proportions with corresponding 95% confidence intervals. Results: In total 227 infants were included, of which 115 were born in 2018 and included in the primary objective analysis. Infant and maternal characteristics were similar for the 2016 and 2018 cohorts. Complete framework adherence was achieved in 54% (n=90) of infants 1000-1499g, 42% (n=12) of infants 800-999g, and no infants of 500-799g were managed with complete adherence. Adherence to ≥80% of recommendations was achieved in 69% of infants. For the secondary objectives, survival to discharge (73.2% in 2016 vs 71.9% in 2018) and 1 year (70.5% in 2016 vs 70.4% in 2018) did not change significantly after Framework implementation. Clinically meaningful reductions in neonatal readmissions (30.6% in 2016 vs 23.5% in 2018) and length of stay (33 days in 2016 vs 28 days in 2018) were observed from 2016 to 2018. Conclusions: The majority of VLBW infants at WPH in 2018 were managed with ≥80% adherence to the Framework, but considerable differences in adherence were noted by birthweight categories. A clinically important decreased length of neonatal stay and readmission were observed postimplementation; this in combination with no increase in mortality represents a potential gain for a resource-restricted healthcare system. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2022-11-17T11:45:17Z 2023-01-16T12:53:04Z 2022-11-17T11:45:17Z 2023-01-16T12:53:04Z 2022-08 Thesis http://hdl.handle.net/10019.1/126158 en_ZA Stellenbosch University 56 pages application/pdf Stellenbosch : Stellenbosch University
spellingShingle Birth weight, Low -- Worcester (South Africa)
Newborn infants -- Mortality -- Worcester (South Africa)
Prematurely born children -- Worcester (South Africa)
Neonatology -- Worcester (South Africa)
UCTD
Van der Merwe, Carine
Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework
title Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework
title_full Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework
title_fullStr Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework
title_full_unstemmed Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework
title_short Analysis of care received by very-low-birthweight neonates at Worcester Provincial Hospital in 2018 after implementation of the Western Cape Provincial Peri-viability Decision Support Framework
title_sort analysis of care received by very low birthweight neonates at worcester provincial hospital in 2018 after implementation of the western cape provincial peri viability decision support framework
topic Birth weight, Low -- Worcester (South Africa)
Newborn infants -- Mortality -- Worcester (South Africa)
Prematurely born children -- Worcester (South Africa)
Neonatology -- Worcester (South Africa)
UCTD
url http://hdl.handle.net/10019.1/126158
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