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Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study
Thesis (PhD) -- Stellenbosch University, 2022.
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| Format: | Thesis |
| Language: | en_ZA |
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Stellenbosch : Stellenbosch University, 2022
2023
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| _version_ | 1867613924421009408 |
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| access_status_str | Open Access |
| author | Sheehama, Ilona Ndapewa |
| author2 | Botha, Matthys Hendrik |
| author_browse | Botha, Matthys Hendrik Sheehama, Ilona Ndapewa |
| author_facet | Botha, Matthys Hendrik Sheehama, Ilona Ndapewa |
| author_sort | Sheehama, Ilona Ndapewa |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (PhD) -- Stellenbosch University, 2022. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/126390 |
| institution | Stellenbosch University (South Africa) |
| language | en_ZA |
| last_indexed | 2026-06-10T12:43:52.525Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Stellenbosch : Stellenbosch University, 2022 |
| publisherStr | Stellenbosch : Stellenbosch University, 2022 |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/126390 Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study Sheehama, Ilona Ndapewa Botha, Matthys Hendrik Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. Obstetrics and Gynaecology. Pulmonary embolism Pregnancy -- Complications Puerperium Ventilation-perfusion ratio Thesis (PhD) -- Stellenbosch University, 2022. ENGLISH ABSTRACT: Background Although pulmonary embolism (PE) is one of the leading causes of death in pregnancy and postpartum, it has low risk of adverse outcome if diagnosed early and treated appropriately. Ventilation-perfusion scanning (VQ scan) or computed tomography pulmonary angiogram (CTPA) are widely used to confirm or diagnose PE, however it carries risks to the mother and the fetus. Up to date, there is no validated clinical predicting tool that can be used in pregnancy and postpartum, thus clinicians face a challenge when suspecting PE in pregnancy and postpartum. Furthermore, the lack of medical resources in low resource environments contributes to the delay of investigations and diagnosis of PE. This study aimed to describe clinical markers for suspicious PE amongst pregnant mothers and immediate postpartum and to design a practical, clinical tool for accurate diagnosis of PE peripartum in our population. Methods The study was performed as a retrospective and analytical study over a period of four months, in the Obstetric Unit at Tygerberg Academic Hospital. The files (total 100) of the patients who were suspected of having PE and underwent imaging (VQ scan or CTPA) were retrospectively evaluated (ECM) to see if there was an association between clinical presentation and PE. All obstetric patients who were imaged for suspected PE, antenatal and immediate postpartum admitted to F2, C2A, OCCU, J2, J4 and J5 were included but not any patients already known with PE or varicose thrombosis. Results There was a statistically significant (P <0.05) association between PE occurrence and ten assessed factors (surgery in <4/52, immobilization >3/7, SOB, hemoptysis, sudden onset of pleuritic chest pain, respiratory alkalosis, sinus tachycardia, deep S1, Q3/T3 and HIV). Conclusion The researcher designed a clinical PE predicting tool that may be used in pregnancy and postpartum. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Doctoral 2023-01-26T06:48:17Z 2023-01-26T06:48:17Z 2022-12 Thesis http://hdl.handle.net/10019.1/126390 en_ZA Stellenbosch University v, 35 pages application/pdf Stellenbosch : Stellenbosch University, 2022 |
| spellingShingle | Pulmonary embolism Pregnancy -- Complications Puerperium Ventilation-perfusion ratio Sheehama, Ilona Ndapewa Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study |
| title | Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study |
| title_full | Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study |
| title_fullStr | Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study |
| title_full_unstemmed | Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study |
| title_short | Clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period: a retrospective, analytical study |
| title_sort | clinical predictors of pulmonary embolism in pregnancy and immediate postpartum period a retrospective analytical study |
| topic | Pulmonary embolism Pregnancy -- Complications Puerperium Ventilation-perfusion ratio |
| url | http://hdl.handle.net/10019.1/126390 |
| work_keys_str_mv | AT sheehamailonandapewa clinicalpredictorsofpulmonaryembolisminpregnancyandimmediatepostpartumperiodaretrospectiveanalyticalstudy |