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Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework
Thesis (MPhil)--Stellenbosch University, 2023.
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| Format: | Thesis |
| Language: | en_ZA en_ZA |
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Stellenbosch : Stellenbosch University
2023
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| _version_ | 1867613763104931840 |
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| access_status_str | Open Access |
| author | Seedat, Soraya |
| author2 | Van Niekerk, Anton A.
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| author_browse | Seedat, Soraya Van Niekerk, Anton A. |
| author_facet | Van Niekerk, Anton A.
Seedat, Soraya |
| author_sort | Seedat, Soraya |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (MPhil)--Stellenbosch University, 2023. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/128807 |
| institution | Stellenbosch University (South Africa) |
| language | en_ZA en_ZA |
| last_indexed | 2026-06-10T12:41:18.607Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/128807 Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework Seedat, Soraya Van Niekerk, Anton A. Stellenbosch University. Faculty of Arts and Social Sciences. Dept. of Philosophy. Applied Ethics. Post-traumatic stress disorder -- Prevention Preventive health services Bioethics Thesis (MPhil)--Stellenbosch University, 2023. ENGLISH ABSTRACT: Preventive interventions for posttraumatic stress disorder (PTSD) hold significant promise for preventing, modifying, and delaying the development of the disorder. Even when preventive interventions have incontrovertible evidence of efficacy and safety, and are widely available in clinical and community settings, which is not yet the status quo in the field of traumatic stress, there are unique ethical and pragmatic concerns to delivering early interventions, given the fact that there is a narrow time window of opportunity to intervene. Amidst the myriad of ethical complexities facing preclinical interventions for PTSD, of primary importance are the inherent ethical challenges linked to false-positive identification and the risks linked to identifying at-risk individuals, and the impact of memory modulating interventions on memory recall and personal identity, and the social implications associated with early intervention. In deliberating these issues, this thesis distills the current state-of-theart of prevention science in PTSD. Innovative interventions that have been investigated, and those in the development pipeline, carry with them unique ethical conundrums that can only be properly addressed and resolved through reflection of the range of ethical and moral theories and principles that inform mental health research and care. While there is a significant body of scholarship on the preventive science of PTSD, and on the ethical quandaries of memory modulation, addressing the wider attendant ethical issues of preventing PTSD through the development of consensus bioethical frameworks, co-produced by mental health researchers, clinicians, other health care providers, and individuals with lived experience of trauma and their families, will allow for true advances to be made towards optimising the benefits and minimising the risks of preventive interventions. AFRIKAANSE OPSOMMING: Voorkomende intervensies vir posttraumatiese stresversteuring (PTSD) hou beduidende belofte in om die ontwikkeling van die versteuring te voorkom, te wysig en te vertraag. Selfs wanneer voorkomende intervensies onbetwisbare bewyse van doeltreffendheid en veiligheid het, en wyd beskikbaar is in kliniese en gemeenskapsomgewings, wat nog nie die status quo in die veld van traumatiese stres is nie, is daar unieke etiese en pragmatiese bekommernisse oor die lewering van vroeë intervensies, gegewe die feit dat daar 'n nou tyd venster van geleentheid is om in te gryp. Te midde van die magdom etiese kompleksiteite wat prekliniese intervensies vir PTSV in die gesig staar, is van primêre belang die inherente etiese uitdagings gekoppel aan vals-positiewe identifikasie en die risiko's verbonde aan die identifisering van individue in gevaar, en die impak van geheue-modulerende intervensies op geheue-herroeping en persoonlike identiteit, en die sosiale implikasies wat verband hou met vroeë intervensie. Deur hierdie kwessies te beraadslaag, distilleer hierdie proefskrif die huidige stand-van-die-kuns van voorkomingswetenskap in PTSV. Innoverende intervensies wat ondersoek is, en dié wat in die ontwikkelingspyplyn is, dra unieke etiese probleme saam wat slegs behoorlik aangespreek en opgelos kan word deur weerspieëling van die reeks etiese en morele teorieë en beginsels wat geestesgesondheidsnavorsing en -sorg inlig. Alhoewel daar 'n beduidende hoeveelheid navorsing is oor die voorkomende wetenskap van PTSV, en oor die etiese kwessies van geheuemodulasie, wat die breër gepaardgaande etiese kwessies van die voorkoming van PTSV aanspreek deur die ontwikkeling van konsensus bioetiese raamwerke, saamgeproduseer deur geestesgesondheidsnavorsers, klinici, sal ander gesondheidsorgverskaffers en individue met geleefde ervaring van trauma en hul gesinne voorsiening maak vir werklike vordering om die voordele te optimaliseer en die risiko's van voorkomende intervensies te verminder. Masters 2023-07-10T08:02:55Z 2024-01-08T11:50:54Z 2023-07-10T08:02:55Z 2024-01-08T11:50:54Z 2023-12 Thesis https://scholar.sun.ac.za/handle/10019.1/128807 en_ZA en_ZA Stellenbosch University 76 pages application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Post-traumatic stress disorder -- Prevention Preventive health services Bioethics Seedat, Soraya Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework |
| title | Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework |
| title_full | Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework |
| title_fullStr | Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework |
| title_full_unstemmed | Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework |
| title_short | Therapeutic prevention of posttraumatic stress disorder: an ethical analysis and proposal of a bioethical framework |
| title_sort | therapeutic prevention of posttraumatic stress disorder an ethical analysis and proposal of a bioethical framework |
| topic | Post-traumatic stress disorder -- Prevention Preventive health services Bioethics |
| url | https://scholar.sun.ac.za/handle/10019.1/128807 |
| work_keys_str_mv | AT seedatsoraya therapeuticpreventionofposttraumaticstressdisorderanethicalanalysisandproposalofabioethicalframework |