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Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics

Thesis (MMed)--Stellenbosch University, 2023.

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Bibliographic Details
Main Author: Farmer, Catherine
Other Authors: Niehaus, Daniel Jan Hendrik
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2023
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access_status_str Open Access
author Farmer, Catherine
author2 Niehaus, Daniel Jan Hendrik
author_browse Farmer, Catherine
Niehaus, Daniel Jan Hendrik
author_facet Niehaus, Daniel Jan Hendrik
Farmer, Catherine
author_sort Farmer, Catherine
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MMed)--Stellenbosch University, 2023.
format Thesis
id oai:scholar.sun.ac.za:10019.1/129091
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:45:32.686Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/129091 Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics Farmer, Catherine Niehaus, Daniel Jan Hendrik Koen, Liezl Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Psychiatry. Psychotropic drugs -- South Africa Mental illness -- Treatment -- South Africa Mental illness in pregnancy -- South Africa Pregnant women -- Mental health -- South Africa UCTD Thesis (MMed)--Stellenbosch University, 2023. ENGLISH SUMMARY: Background: There is a significant burden of mental illness during pregnancy and the safety of medication use in pregnancy is an ongoing focus of research. There is potential risk for the developing fetus and the mother from the increased risk for psychiatric illness and medication effects. Psychotropic polypharmacy during pregnancy is common, but not well- researched and there is a paucity of data on the use of psychotropic medication during pregnancy in South African women suffering from a mental illness. Aim: To determine the psychotropic medication prescription patterns in pregnant patients attending one of two maternal mental health clinics in Cape Town in terms of: the general classes of medication prescribed, the frequency and duration of psychotropic use, medication exposure according to pregnancy trimester and the prevalence of polypharmacy use. Methods: Pregnant women attending two maternal mental health clinics were studied from presentation to six weeks postpartum. Demographic data, psychiatric history, medical comorbid illnesses, pregnancy related data and medication prescription was collected and tabulated at treatment-as-usual visits. Polypharmacy prevalence was determined by using the definition of the use of two or more psychotropic medication prescriptions for a period of at least ninety days. Results: Data was collected on 303 pregnancies and the majority of pregnant women (51.8%) were diagnosed with major depressive disorder. Anti-depressant medication was the most commonly prescribed medication class (64.3%). A third of participants received prescriptions in all three trimesters. Polypharmacy criteria was met in 18.8% of the sample population. Conclusion: Prescribing psychotropic drugs in pregnancy is challenging because of the need to weigh up the potential risks of drug- related effects on the mother and child against those of discontinuing treatment. Our data contributes to raising awareness and aids medical professionals with regards to the rational use of psychotropic medication in pregnant women. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2023-11-28T12:28:13Z 2024-01-08T22:04:46Z 2023-11-28T12:28:13Z 2024-01-08T22:04:46Z 2023-12 Thesis https://scholar.sun.ac.za/handle/10019.1/129091 en_ZA Stellenbosch University 33 unnumbered pages application/pdf Stellenbosch : Stellenbosch University
spellingShingle Psychotropic drugs -- South Africa
Mental illness -- Treatment -- South Africa
Mental illness in pregnancy -- South Africa
Pregnant women -- Mental health -- South Africa
UCTD
Farmer, Catherine
Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics
title Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics
title_full Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics
title_fullStr Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics
title_full_unstemmed Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics
title_short Psychotropic medication prescribing patterns during pregnancy in two South African Maternal Mental Health clinics
title_sort psychotropic medication prescribing patterns during pregnancy in two south african maternal mental health clinics
topic Psychotropic drugs -- South Africa
Mental illness -- Treatment -- South Africa
Mental illness in pregnancy -- South Africa
Pregnant women -- Mental health -- South Africa
UCTD
url https://scholar.sun.ac.za/handle/10019.1/129091
work_keys_str_mv AT farmercatherine psychotropicmedicationprescribingpatternsduringpregnancyintwosouthafricanmaternalmentalhealthclinics