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Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study

Thesis (MSc)--Stellenbosch University, 2023.

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Main Author: Van Niekerk, Hendrik Jacques
Other Authors: McCaul, Michael
Format: Thesis
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2024
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access_status_str Open Access
author Van Niekerk, Hendrik Jacques
author2 McCaul, Michael
author_browse McCaul, Michael
Van Niekerk, Hendrik Jacques
author_facet McCaul, Michael
Van Niekerk, Hendrik Jacques
author_sort Van Niekerk, Hendrik Jacques
collection Thesis
dc_rights_str_mv Stellenbosch University
description Thesis (MSc)--Stellenbosch University, 2023.
format Thesis
id oai:scholar.sun.ac.za:10019.1/129327
institution Stellenbosch University (South Africa)
language en_ZA
last_indexed 2026-06-10T12:42:41.823Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/129327 Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study Van Niekerk, Hendrik Jacques McCaul, Michael Rohwer, Anke Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Global Health. Epidemiology and Biostatistics. Systematic reviews (Medical research) Emergency medicine -- Periodicals Outcome assessment (Medical care) UCTD Thesis (MSc)--Stellenbosch University, 2023. The published article for this Master's thesis is available at: https://www.sciencedirect.com ENGLISH SUMMARY: Introduction: Reliable systematic reviews are essential to inform clinical practice guidelines, policies and further research priorities in Africa. For systematic review findings to be trustworthy, they need to be conducted with methodological rigour and reported transparently. We assessed the methodological quality of systematic reviews published in African emergency medicine journals, comparing them to those published in international emergency medicine journals. Additionally, we describe the types of review literature published in the African journals. Methods: We performed a cross-sectional methodological study of systematic reviews published in selected African and international emergency medicine journals from 2012 to 2021. Studies were eligible for inclusion if they were i) published in one of the top five emergency medicine journals in the African region or internationally, ii) a review article on an emergency medicine topic and iii) published between January 2012 and December 2021 in English or French. We searched PubMed, Web of Science and Scopus databases and hand-searched selected journals. Two authors screened titles, abstracts and full texts independently and in duplicate to select reviews for inclusion. Data extraction was performed by one reviewer, using a standardised form, after completing a calibration exercise. We described the characteristics of systematic reviews and assessed methodological quality using AMSTAR II. Results: We identified 34 (37%) African and 511 (54%) international systematic reviews from 92 and 948 review articles respectively across 10 journals. We included all 34 African and a random sample of 100 international systematic reviews. Methodological quality was low or critically low for all the African systematic reviews (n=34, 100%) and all but three international systematic reviews (n=97, 97%). The median number of critical domain weaknesses was 4 (IQR 4;5) and 2 (IQR 2;4) for African and international systematic reviews respectively. The most common weaknesses across both African and international systematic reviews were i) not establishing a priori review protocols, ii) unclear selection of study designs iii) not providing a list of excluded studies and iv) unclear reporting on funding sources for included studies. Conclusion: Emergency medicine systematic reviews published in African and international journals are lacking in methodological quality. Reporting an a priori protocol, developing a comprehensive search strategy, appropriate evidence synthesis and adequate assessment of the risk of bias, heterogeneity and evidence certainty will improve the quality of systematic reviews. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2024-02-20T07:40:37Z 2023-03-08T14:01:28Z 2024-02-20T07:40:37Z 2023-03-08T14:01:28Z 2023-03 Thesis https://scholar.sun.ac.za/handle/10019.1/129327 en_ZA Stellenbosch University 157 pages ; includes annexures application/pdf Stellenbosch : Stellenbosch University
spellingShingle Systematic reviews (Medical research)
Emergency medicine -- Periodicals
Outcome assessment (Medical care)
UCTD
Van Niekerk, Hendrik Jacques
Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study
title Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study
title_full Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study
title_fullStr Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study
title_full_unstemmed Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study
title_short Quality of systematic reviews in African emergency medicine : a cross-sectional methodological study
title_sort quality of systematic reviews in african emergency medicine a cross sectional methodological study
topic Systematic reviews (Medical research)
Emergency medicine -- Periodicals
Outcome assessment (Medical care)
UCTD
url https://scholar.sun.ac.za/handle/10019.1/129327
work_keys_str_mv AT vanniekerkhendrikjacques qualityofsystematicreviewsinafricanemergencymedicineacrosssectionalmethodologicalstudy