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The role of fluoroquinolone-induced bacterial stress responses in the development of antimicrobial resistance
Introduction: In response to quinolone-induced DNA damage, bacteria induce the SOS response to repair the damage, which can lead to development of antimicrobial resistance (AMR) via increased mutagenesis. N-acetyl-cysteine (NAC) has been demonstrated to suppress the ciprofloxacin (CIP)-induced SOS r...
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| Format: | Thesis |
| Language: | en_ZA |
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Stellenbosch University
2025
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