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Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks
Hanekom, W. 2025. Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/26e3a257-f4ff-4254-a54b-af57a783ae...
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Stellenbosch : Stellenbosch University
2025
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| _version_ | 1867613789721985024 |
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| access_status_str | Open Access |
| author | Hanekom, Werner |
| author2 | Van der Merwe, Johan |
| author_browse | Hanekom, Werner Van der Merwe, Johan |
| author_facet | Van der Merwe, Johan Hanekom, Werner |
| author_sort | Hanekom, Werner |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Hanekom, W. 2025. Development of an automated method for
generating patient-specific mandible reconstruction
plates based on mandibular landmarks. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/26e3a257-f4ff-4254-a54b-af57a783aef5 |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/132407 |
| institution | Stellenbosch University (South Africa) |
| last_indexed | 2026-06-10T12:41:43.824Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/132407 Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks Hanekom, Werner Van der Merwe, Johan Stellenbosch University. Faculty of Engineering. Dept. of Mechanical and Mechatronic Engineering. Mandible -- Surgery Medical technologists Maxilla -- Surgery Three-dimensional modeling UCTD Hanekom, W. 2025. Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/26e3a257-f4ff-4254-a54b-af57a783aef5 Thesis (MEng)--Stellenbosch University, 2025. ENGLISH ABSTRACT: This thesis introduces a framework capable of generating reconstruction plates for various mandible and defect geometries, which may facilitate personalised maxillofacial surgery treatment approaches. A 3D model database was created from the CT scans of 44 healthy human mandibles. The 3D models were used for identifying mandibular landmarks and documenting their coordinates. A random forest regressor model was developed to predict missing mandibular landmarks in cases of incomplete geometry. To simulate this, artificial defects were considered through the removal of coordinates. The data was split into an 80:20 ratio for training and testing. The model was trained on a variety of hyperparameters and tested to determine the model’s accuracy. This was done for two defect classes: class II- and class IV defects. The root mean squared error values achieved were 2.795 mm and 2.272 mm for the class II- and class IV defects respectively. Using the documented landmark coordinates, CAD software was used for the reconstruction plate design. A VBA script was created which can generate these plates automatically based on the imported coordinates of a single mandible. The script was used to generate plates for all the mandibles in the 3D model database and were used along with their respective mandibles to evaluate the fit, which led to an average root mean squared value of 2.403 mm, which indicates a good fit. Validation of the design was done through an FEA study for both defect classes. A single reference mandible was used based on the median sized mandible in the 3D model database. This process was used to refine the reconstruction plate design, particularly focusing on minimising stress concentrations and enhancing overall structural integrity. The maximum stress values obtained were 250.8 MPa and 22.24 MPa for the class II- and class IV defects respectively which compare well with the relevant literature. AFRIKAANSE OPSOMMING: Hierdie tesis behels ‘n raamwerk wat in staat is om rekonstruksieplate te genereer vir verskeie kakebeen- en defekgeometrieë wat persoonlike maksillofasiale chirurgiese behandelingsbenaderings kan fasiliteer. 'n 3D-model databasis was geskep uit rekenaartomografiese skanderings van 44 gesonde menslike kakebene en was gebruik om landmerke te identifiseer en hul koördinate te dokumenteer. 'n Lukrake woudregressiemodel was ontwikkel om ontbrekende mandibulêre landmerke te voorspel in gevalle van onvolledige geometrie. Om dit te simuleer, was kunsmatige defekte oorweeg deur koördinate te verwyder. Die data was verdeel in 'n 80:20 verhouding vir opleiding en toetsing. Dit was gedoen vir twee defekklasse: klas II- en klas IV defekte. Die vierkantswortel van die gemiddelde kwadraatfout waardes wat bereik was, was onderskeidelik 2.795 mm en 2.272 mm vir die klas II- en klas IV defekte. Met die gedokumenteerde landmerkkoördinate was sagteware gebruik vir die rekonstruksieplaat ontwerp. ’n VBA-program was geskep wat die plate outomaties genereer gebaseer op die ingevoerde koördinate van ’n enkele kakebeen. Die program was gebruik om rekonstruksieplate vir al die kakebene in die databasis te genereer en was saam met hul onderskeie kakebene gebruik om die passing te evalueer, wat gelei het tot ‘n gemiddelde afwyking van 2.403 mm. Validering van die ontwerp was gedoen deur middel van 'n eindige element analise vir beide defekklasse. ’n Enkele verwysingskakebeen was gebruik gebaseer op die mediaan-grootte kakebeen in die 3D-model databasis. Hierdie proses was gebruik om die ontwerp te verfyn, veral met fokus op die vermindering van spanningskonsentrasies en verbetering van strukturele integriteit. Die maksimum spanningswaardes wat verkry was, was 250.8 MPa en 22.24 MPa vir die klas II- en klas IV defekte onderskeidelik, wat goed vergelyk met die toepaslike literatuur. Masters 2025-06-06T07:46:12Z 2025-06-06T07:46:12Z 2025-03 Thesis https://scholar.sun.ac.za/handle/10019.1/132407 Stellenbosch University xi, 79 pages : illustrations application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Mandible -- Surgery Medical technologists Maxilla -- Surgery Three-dimensional modeling UCTD Hanekom, Werner Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks |
| title | Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks |
| title_full | Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks |
| title_fullStr | Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks |
| title_full_unstemmed | Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks |
| title_short | Development of an automated method for generating patient-specific mandible reconstruction plates based on mandibular landmarks |
| title_sort | development of an automated method for generating patient specific mandible reconstruction plates based on mandibular landmarks |
| topic | Mandible -- Surgery Medical technologists Maxilla -- Surgery Three-dimensional modeling UCTD |
| url | https://scholar.sun.ac.za/handle/10019.1/132407 |
| work_keys_str_mv | AT hanekomwerner developmentofanautomatedmethodforgeneratingpatientspecificmandiblereconstructionplatesbasedonmandibularlandmarks |