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Shiba, S. L. 2025. Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/2b3c144c-4368-4a18-8ec1-f3c3...
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| Format: | Thesis |
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Stellenbosch : Stellenbosch University
2025
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| _version_ | 1867613797569527808 |
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| access_status_str | Open Access |
| author | Shiba, Sakhele Lancelort |
| author2 | Trauernicht, Christoph Jan |
| author_browse | Shiba, Sakhele Lancelort Trauernicht, Christoph Jan |
| author_facet | Trauernicht, Christoph Jan Shiba, Sakhele Lancelort |
| author_sort | Shiba, Sakhele Lancelort |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Shiba, S. L. 2025. Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/2b3c144c-4368-4a18-8ec1-f3c311437392 |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/133091 |
| institution | Stellenbosch University (South Africa) |
| last_indexed | 2026-06-10T12:41:51.674Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/133091 Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms Shiba, Sakhele Lancelort Trauernicht, Christoph Jan Robar, James Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Medical Imaging and Clinical Oncology. Brain -- Cancer -- Radiotherapy Stereotaxic techniques Metastasis -- Treatment UCTD Shiba, S. L. 2025. Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/2b3c144c-4368-4a18-8ec1-f3c311437392 Thesis (MSc)--Stellenbosch University, 2025. ENGLISH ABSTRACT: Purpose: C-arm linacs have been used widely to treat multiple cranial metastases using stereotactic radiosurgery (SRS). A new generation of O-ring linacs offer several workflow advantages when compared to C-arm platforms. However, O-ring linacs are not able to employ couch rotations for non-coplanar beams used in SRS treatments. This study was conducted in order to simulate further possible developments of O-ring treatment units by assessing their geometrical efficiency. In this work we compare the plan quality for C-arm versus an O-ring platform including metrics that are relevant to SRS for multiple metastases. The comparison is conducted by incorporating tilted arcs on the O-ring platform therefore introducing non-coplanarity. Methods: 40 patients previously treated for SRS with 20 Gy single fraction were replanned for C-arm with a standard non-coplanar 5-arc arrangement and O-ring with both coplanar and non-coplanar beams. For the O-ring plans, we considered a default 3-arc co-planar arrangement, as well as 3- and 5-arc arrangements with arcs tipped up to 10 degrees from the axial plane. Target coverage, organ-at-risk (OAR) doses, monitor unit (MU) efficiency, conformity and gradient indices were assessed for all plans. Results: For most metrics the O-ring geometries, even the co-planar arrangement, produced statistically comparable results to the C-arm. Small but significant differences were found for the 3 arc O-ring for PTV: D90%, D2% and MU/Gy and for the 5 arc O-ring at D2% when both were compared to the C-arm. Cumulative dose volume histograms (DVHs) for normal brain showed a cross-over between the C-arm and coplanar O-ring geometry at a low dose (2.3 1.8 Gy), with O-ring associated with higher volumes above this cross-over dose. However, no statistical difference was seen in the brainstem, optic pathway and volumes of normal brain receiving 12 Gy or 20 Gy. Conclusion: This study has found that O-ring geometry linacs can produce SRS plans of comparable quality to those from a C-arm for multiple cranial metastases. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2025-07-17T10:51:59Z 2025-07-17T10:51:59Z 2025-03 Thesis https://scholar.sun.ac.za/handle/10019.1/133091 Stellenbosch University vi, 36 pages : illustrations application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Brain -- Cancer -- Radiotherapy Stereotaxic techniques Metastasis -- Treatment UCTD Shiba, Sakhele Lancelort Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms |
| title | Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms |
| title_full | Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms |
| title_fullStr | Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms |
| title_full_unstemmed | Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms |
| title_short | Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms |
| title_sort | treatment plan quality for stereotactic treatment of multiple cranial metastases comparison of c arm and o ring treatment platforms |
| topic | Brain -- Cancer -- Radiotherapy Stereotaxic techniques Metastasis -- Treatment UCTD |
| url | https://scholar.sun.ac.za/handle/10019.1/133091 |
| work_keys_str_mv | AT shibasakhelelancelort treatmentplanqualityforstereotactictreatmentofmultiplecranialmetastasescomparisonofcarmandoringtreatmentplatforms |