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Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms

Shiba, S. L. 2025. Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/2b3c144c-4368-4a18-8ec1-f3c3...

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Main Author: Shiba, Sakhele Lancelort
Other Authors: Trauernicht, Christoph Jan
Format: Thesis
Published: Stellenbosch : Stellenbosch University 2025
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access_status_str Open Access
author Shiba, Sakhele Lancelort
author2 Trauernicht, Christoph Jan
author_browse Shiba, Sakhele Lancelort
Trauernicht, Christoph Jan
author_facet Trauernicht, Christoph Jan
Shiba, Sakhele Lancelort
author_sort Shiba, Sakhele Lancelort
collection Thesis
dc_rights_str_mv Stellenbosch University
description Shiba, S. L. 2025. Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/2b3c144c-4368-4a18-8ec1-f3c311437392
format Thesis
id oai:scholar.sun.ac.za:10019.1/133091
institution Stellenbosch University (South Africa)
last_indexed 2026-06-10T12:41:51.674Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository
publishDate 2025
publishDateRange 2025
publishDateSort 2025
publisher Stellenbosch : Stellenbosch University
publisherStr Stellenbosch : Stellenbosch University
record_format dspace
source_str SUNScholar — Stellenbosch University Repository
spelling oai:scholar.sun.ac.za:10019.1/133091 Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms Shiba, Sakhele Lancelort Trauernicht, Christoph Jan Robar, James Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Medical Imaging and Clinical Oncology. Brain -- Cancer -- Radiotherapy Stereotaxic techniques Metastasis -- Treatment UCTD Shiba, S. L. 2025. Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms. Unpublished masters thesis. Stellenbosch: Stellenbosch University [online]. Available: https://scholar.sun.ac.za/items/2b3c144c-4368-4a18-8ec1-f3c311437392 Thesis (MSc)--Stellenbosch University, 2025. ENGLISH ABSTRACT: Purpose: C-arm linacs have been used widely to treat multiple cranial metastases using stereotactic radiosurgery (SRS). A new generation of O-ring linacs offer several workflow advantages when compared to C-arm platforms. However, O-ring linacs are not able to employ couch rotations for non-coplanar beams used in SRS treatments. This study was conducted in order to simulate further possible developments of O-ring treatment units by assessing their geometrical efficiency. In this work we compare the plan quality for C-arm versus an O-ring platform including metrics that are relevant to SRS for multiple metastases. The comparison is conducted by incorporating tilted arcs on the O-ring platform therefore introducing non-coplanarity. Methods: 40 patients previously treated for SRS with 20 Gy single fraction were replanned for C-arm with a standard non-coplanar 5-arc arrangement and O-ring with both coplanar and non-coplanar beams. For the O-ring plans, we considered a default 3-arc co-planar arrangement, as well as 3- and 5-arc arrangements with arcs tipped up to 10 degrees from the axial plane. Target coverage, organ-at-risk (OAR) doses, monitor unit (MU) efficiency, conformity and gradient indices were assessed for all plans. Results: For most metrics the O-ring geometries, even the co-planar arrangement, produced statistically comparable results to the C-arm. Small but significant differences were found for the 3 arc O-ring for PTV: D90%, D2% and MU/Gy and for the 5 arc O-ring at D2% when both were compared to the C-arm. Cumulative dose volume histograms (DVHs) for normal brain showed a cross-over between the C-arm and coplanar O-ring geometry at a low dose (2.3  1.8 Gy), with O-ring associated with higher volumes above this cross-over dose. However, no statistical difference was seen in the brainstem, optic pathway and volumes of normal brain receiving 12 Gy or 20 Gy. Conclusion: This study has found that O-ring geometry linacs can produce SRS plans of comparable quality to those from a C-arm for multiple cranial metastases. AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar. Masters 2025-07-17T10:51:59Z 2025-07-17T10:51:59Z 2025-03 Thesis https://scholar.sun.ac.za/handle/10019.1/133091 Stellenbosch University vi, 36 pages : illustrations application/pdf Stellenbosch : Stellenbosch University
spellingShingle Brain -- Cancer -- Radiotherapy
Stereotaxic techniques
Metastasis -- Treatment
UCTD
Shiba, Sakhele Lancelort
Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms
title Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms
title_full Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms
title_fullStr Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms
title_full_unstemmed Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms
title_short Treatment plan quality for stereotactic treatment of multiple cranial metastases: comparison of C-arm and O-ring treatment platforms
title_sort treatment plan quality for stereotactic treatment of multiple cranial metastases comparison of c arm and o ring treatment platforms
topic Brain -- Cancer -- Radiotherapy
Stereotaxic techniques
Metastasis -- Treatment
UCTD
url https://scholar.sun.ac.za/handle/10019.1/133091
work_keys_str_mv AT shibasakhelelancelort treatmentplanqualityforstereotactictreatmentofmultiplecranialmetastasescomparisonofcarmandoringtreatmentplatforms