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Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes?
Thesis (DMed (Psychiatry))--University of Stellenbosch, 2005.
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| Format: | Thesis |
| Language: | English |
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Stellenbosch : University of Stellenbosch
2006
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| _version_ | 1867614032751493120 |
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| access_status_str | Open Access |
| author | Niehaus, Daniel Jan Hendrik |
| author2 | Emsley, R. A. |
| author_browse | Emsley, R. A. Niehaus, Daniel Jan Hendrik |
| author_facet | Emsley, R. A. Niehaus, Daniel Jan Hendrik |
| author_sort | Niehaus, Daniel Jan Hendrik |
| collection | Thesis |
| dc_rights_str_mv | University of Stellenbosch |
| description | Thesis (DMed (Psychiatry))--University of Stellenbosch, 2005. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/1435 |
| institution | Stellenbosch University (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:45:35.384Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2006 |
| publishDateRange | 2006 |
| publishDateSort | 2006 |
| publisher | Stellenbosch : University of Stellenbosch |
| publisherStr | Stellenbosch : University of Stellenbosch |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/1435 Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? Niehaus, Daniel Jan Hendrik Emsley, R. A. Jordaan, E. University of Stellenbosch. Faculty of Health Sciences. Dept. of Psychiatry. Schizophrenia -- South Africa -- Genetic aspects Xhosa (African people) -- Mental health -- South Africa Dissertations -- Psychiatry Theses -- Psychiatry Thesis (DMed (Psychiatry))--University of Stellenbosch, 2005. BACKGROUND Schizophrenia is a heterogeneous disorder, which has been shown to have both environmental and genetic risk factors. Since family history (genetic loading) of psychosis appears to be one of the strongest risk factors for the development of schizophrenia, the investigation of affected sib pairs can be used to explore shared familial factors. The Xhosa-speaking inhabitants in the Western, Eastern and Southern Cape provinces, an African population of relatively homogeneous ethnicity, provided a sample of the first large clinical phenotype of schizophrenia. AIM The main aim of this study was to identify shared symptoms or symptom clusters in a sample of Xhosa-speaking sib pairs, with the aid of structured assessment tools. Doctoral 2006-11-13T09:21:08Z 2010-06-01T08:21:30Z 2006-11-13T09:21:08Z 2010-06-01T08:21:30Z 2005-12 Thesis http://hdl.handle.net/10019.1/1435 en University of Stellenbosch 2030280 bytes application/pdf application/pdf Stellenbosch : University of Stellenbosch |
| spellingShingle | Schizophrenia -- South Africa -- Genetic aspects Xhosa (African people) -- Mental health -- South Africa Dissertations -- Psychiatry Theses -- Psychiatry Niehaus, Daniel Jan Hendrik Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? |
| title | Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? |
| title_full | Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? |
| title_fullStr | Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? |
| title_full_unstemmed | Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? |
| title_short | Limiting clinical heterogeneity in schizophrenia : can affected Xhosa sib pairs provide valid subtypes? |
| title_sort | limiting clinical heterogeneity in schizophrenia can affected xhosa sib pairs provide valid subtypes |
| topic | Schizophrenia -- South Africa -- Genetic aspects Xhosa (African people) -- Mental health -- South Africa Dissertations -- Psychiatry Theses -- Psychiatry |
| url | http://hdl.handle.net/10019.1/1435 |
| work_keys_str_mv | AT niehausdanieljanhendrik limitingclinicalheterogeneityinschizophreniacanaffectedxhosasibpairsprovidevalidsubtypes |