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Development of Pichia pastoris as a production system for HPV16 L1 virus-like particles as component to a subunit vaccine

Human papillomavirus (HPV) is a sexually transmitted virus and known precursor to cervical cancer, the second most lethal cancer in females across the world. Two virus-like particle (VLP) vaccines exist that provide immunity against the main serotypes of the disease and are produced in Saccharomy...

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Bibliographic Details
Main Author: Kotze, Lara
Other Authors: Gorgens, Johann F.
Format: Thesis
Published: Stellenbosch : University of Stellenbosch 2008
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