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An investigation into the biological activity of rooibos (Aspalathus linearis) extracts
Thesis (MSc (Biochemistry))--Stellenbosch University, 2008.
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Stellenbosch : Stellenbosch University
2008
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| _version_ | 1867614102000500736 |
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| access_status_str | Open Access |
| author | Richfield, David |
| author2 | Swart, Amanda C. |
| author_browse | Richfield, David Swart, Amanda C. |
| author_facet | Swart, Amanda C. Richfield, David |
| author_sort | Richfield, David |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (MSc (Biochemistry))--Stellenbosch University, 2008. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/3020 |
| institution | Stellenbosch University (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:46:41.344Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2008 |
| publishDateRange | 2008 |
| publishDateSort | 2008 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/3020 An investigation into the biological activity of rooibos (Aspalathus linearis) extracts Richfield, David Swart, Amanda C. Swart, P. Stellenbosch University. Faculty of Science. Dept. of Biochemistry. Cytochrome P450 Rooibos Endocrinology Polyphenol antioxidants Dissertations -- Biochemistry Theses -- Biochemistry Thesis (MSc (Biochemistry))--Stellenbosch University, 2008. This study describes: 1. The preparation of chloroform, methanol and aqueous extracts of unfermented and fermented rooibos (Aspalathus linearis). 2. The chromatographic fractionation of aqueous rooibos extracts and an investigation into the polyphenol content and antioxidant activity of the fractions. 3. The preparation of ovine adrenal microsomes containing active steroidogenic P450 enzymes, including cytochrome P450 17a-hydroxylase, CYP17, and cytochrome P450 steroid 21-hydroxylase, CYP21. 4. An investigation into the influence of chloroform and methanol extracts of rooibos on the binding of steroid substrates, progesterone and 17-hydroxyprogesterone, to CYP17 and CYP21. 2008-06-23T09:30:21Z 2010-06-01T09:04:09Z 2008-06-23T09:30:21Z 2010-06-01T09:04:09Z 2008-03 Thesis http://hdl.handle.net/10019.1/3020 en Stellenbosch University application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Cytochrome P450 Rooibos Endocrinology Polyphenol antioxidants Dissertations -- Biochemistry Theses -- Biochemistry Richfield, David An investigation into the biological activity of rooibos (Aspalathus linearis) extracts |
| title | An investigation into the biological activity of rooibos (Aspalathus linearis) extracts |
| title_full | An investigation into the biological activity of rooibos (Aspalathus linearis) extracts |
| title_fullStr | An investigation into the biological activity of rooibos (Aspalathus linearis) extracts |
| title_full_unstemmed | An investigation into the biological activity of rooibos (Aspalathus linearis) extracts |
| title_short | An investigation into the biological activity of rooibos (Aspalathus linearis) extracts |
| title_sort | investigation into the biological activity of rooibos aspalathus linearis extracts |
| topic | Cytochrome P450 Rooibos Endocrinology Polyphenol antioxidants Dissertations -- Biochemistry Theses -- Biochemistry |
| url | http://hdl.handle.net/10019.1/3020 |
| work_keys_str_mv | AT richfielddavid aninvestigationintothebiologicalactivityofrooibosaspalathuslinearisextracts AT richfielddavid investigationintothebiologicalactivityofrooibosaspalathuslinearisextracts |