Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia
Thesis (Ph.D.)__University of Stellenbosch, 1993.
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | en_ZA |
| Published: |
Stellenbosch : Stellenbosch University
2012
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867614023649853440 |
|---|---|
| access_status_str | Open Access |
| author | Coetzee, Johannes Francois |
| author2 | Coetzee, A. R. |
| author_browse | Coetzee, A. R. Coetzee, Johannes Francois |
| author_facet | Coetzee, A. R. Coetzee, Johannes Francois |
| author_sort | Coetzee, Johannes Francois |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (Ph.D.)__University of Stellenbosch, 1993. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/57852 |
| institution | Stellenbosch University (South Africa) |
| language | en_ZA |
| last_indexed | 2026-06-10T12:45:26.037Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2012 |
| publishDateRange | 2012 |
| publishDateSort | 2012 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/57852 An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia Coetzee, Johannes Francois Coetzee, A. R. Miller, R. Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Anesthesiology & Critical Care. Intravenous anesthesia Dissertations -- Medicine Thesis (Ph.D.)__University of Stellenbosch, 1993. The anaesthetic, propofol and the opioid, alfentanil have pharmacokinetic profiles suitable for total intravenous anaesthesia. The hypothesis states that they are cardiovascular depressants and that their administration causes haemodynamic instability. A review of the literature is presented wherein the pharmacokinetics and the cardiovascular pharmacodynarnics of the drugs are amplified. Pig pharmacokinetic models for propofol and alfentanil, were determined by applying curve-fitting computer programs to measured post-infusion concentrations and were used by computer-controlled infusions to establish predicted drug concentrations during haemodynamic studies. Doctoral 2012-08-27T11:38:41Z 2012-08-27T11:38:41Z 1993 Thesis http://hdl.handle.net/10019.1/57852 en_ZA Stellenbosch University 364 pages application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Intravenous anesthesia Dissertations -- Medicine Coetzee, Johannes Francois An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| title | An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| title_full | An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| title_fullStr | An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| title_full_unstemmed | An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| title_short | An investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| title_sort | investigation into the cardiovascular effects of propofol and alfentanil for total intravenous anaesthesia |
| topic | Intravenous anesthesia Dissertations -- Medicine |
| url | http://hdl.handle.net/10019.1/57852 |
| work_keys_str_mv | AT coetzeejohannesfrancois aninvestigationintothecardiovasculareffectsofpropofolandalfentanilfortotalintravenousanaesthesia AT coetzeejohannesfrancois investigationintothecardiovasculareffectsofpropofolandalfentanilfortotalintravenousanaesthesia |