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Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing
Thesis (MEng)--Stellenbosch University, 2014.
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| Format: | Thesis |
| Language: | en_ZA |
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Stellenbosch : Stellenbosch University
2014
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| _version_ | 1867613852203483136 |
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| access_status_str | Open Access |
| author | Marcantonio, Graziano |
| author2 | Dimitrov, D. M. |
| author_browse | Dimitrov, D. M. Marcantonio, Graziano |
| author_facet | Dimitrov, D. M. Marcantonio, Graziano |
| author_sort | Marcantonio, Graziano |
| collection | Thesis |
| dc_rights_str_mv | Stellenbosch University |
| description | Thesis (MEng)--Stellenbosch University, 2014. |
| format | Thesis |
| id | oai:scholar.sun.ac.za:10019.1/86243 |
| institution | Stellenbosch University (South Africa) |
| language | en_ZA |
| last_indexed | 2026-06-10T12:42:41.823Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from SUNScholar — Stellenbosch University Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Stellenbosch : Stellenbosch University |
| publisherStr | Stellenbosch : Stellenbosch University |
| record_format | dspace |
| source_str | SUNScholar — Stellenbosch University Repository |
| spelling | oai:scholar.sun.ac.za:10019.1/86243 Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing Marcantonio, Graziano Dimitrov, D. M. Van der Merwe, A. F. Stellenbosch University. Faculty of Engineering. Dept. of Industrial Engineering. Spinal implants Cervical vertebrae -- Surgery Intervertebral disk prostheses Spine -- Surgery Dissertations -- Industrial engineering UCTD Theses -- Industrial engineering Thesis (MEng)--Stellenbosch University, 2014. ENGLISH ABSTRACT: Neck pain is a common phenomenon that occurs in a large percentage of the population every day. While many occurrences are not deemed critical such as those from muscle strain which can be treated with rest and pain medication, others due to sports injuries, whiplash from car accidents, bad posture or degeneration of the intervertebral disc can be quite severe. In extreme cases failure of the vertebra(e) or the intervertebral disc requires surgery and possibly the use of cervical implants. Where intervertebral discs fail due to herniation or Degenerative Disc Disease (DDD), Anterior Cervical Discectomy and Fusion (ACDF) is a common surgical method used to remove the a ected disc and replace it with a cervical cage implant. These implants are designed to restore the height between the vertebrae, allowing bone from both vertebrae to grow through them and mineralise. Additive Manufacturing (AM) technologies can produce parts with complex geometries not possible using conventional manufacturing methods. This design freedom, coupled with CT scans of a patient, allow for tailoring an implant to the speci c anatomy of the a ected vertebrae using CAD software. Such an approach must be regulated and shown to be technically and commercially feasible before it can be implemented in industry. This study sought to develop a framework for manufacturing customized cervical cage implants using additive manufacturing. The e cacy of customization to reduce the risk of subsidence was investigated by means of non-destructive and destructive mechanical testing on six cadaver specimens, using readily available PEEK cage implants as a benchmark. The results showed that the customized implant was comparable to the PEEK, with no statistically signi cant di erence between the two. In extreme cases, where PEEK implants cannot be used, customized implants could be a suitable alternative to reduce the risk of subsidence. A manufacturing cost analysis was conducted to determine economic feasibility. The estimated cost and selling price of the customized implants under various utilization scenarios and mark-ups was compared to readily available PEEK implants. The estimated selling prices of the customized implants compared favourably to the PEEK verifying the economic viability of using AM. AFRIKAANSE OPSOMMING: Nek pyn is 'n algemene verskynsel wat daagliks na tevore kom in die bevolking. Baie gevalle word nie as krities geklasi seer nie soos byvoorbeeld spier pyn wat behandel kan word deur genoegsame rus en pyn medikasie. Pyn wat deur sportbeserings, sweepslag beserings 'whiplash' tydens motor ongelukke, verkeerde postuur, of deur slytasie van 'n intervertebrale skyf veroorsaak is, word dikwels as ernstig geklasi seer. In ekstreme gevalle waar die werwel(s) of die inervertebrale skyf(we) faal, sal chirurgie en servikale inplantate moontlik nodig wees. Waneer intervertebrale skywe faal weens herniatie of Degeneratiewe Skyf Siekte (DDD) kan 'n algemene chirurgiese metode, Anterieure Servikale Discectomie en Fusie (ACDF), gebruik word om die gea ekteerde skyf te verwyder en dit te vervang met 'n servikale samesmelting implantaat. Hierdie implantate herstel die hoogte tussen rugwerwels en is ontwerp sodat die been deur dit kan groei en mineraliseer. Komplekse geometrieë kan vervaardig word deur toevoegingsvervaardiging (AM) tegnologieë. Die ontwerp vryheid, gepaard met CT-skanderings en CAD-sagteware stel mens in staat om die geometrie van die implantaat aan te pas tot die spese eke anatomie van die gea ekteerde vertebra. So 'n benadering moet gereguleer word en eers tegnies en kommersieel uitvoerbaar bewys word voordat dit in die bedryf geïmplementeer kan word. Hierdie studie poog verder om 'n raamwerk vir die vervaardiging van persoonlike servikale implantate deur middel van toevoegingsvervaardiging te ontwikkel. Die doeltre endheid van persoonlike implantate om te verhoed dat die chirurg die eind-plaat beskadig, en sodoende die risiko van insakking te verminder, is ondersoek deur middel van meganiese toetse op ses kadawer monsters. Hierdie toetse is gedoen met behulp van geredelik beskikbaar PEEK servikale implantate as 'n maatstaf. Die resultate het getoon dat die persoonlike- en PEEK implantate vergelykbaar is. In moontlike gevalle waar PEEK implantate nie geskik sou wees nie, kan persoonlike implantate 'n alternatiewe opsie wees om die risiko van insakking te verminder. 2014-04-16T17:28:23Z 2014-04-16T17:28:23Z 2014-04 Thesis http://hdl.handle.net/10019.1/86243 en_ZA Stellenbosch University xv, 115 p. : ill. application/pdf Stellenbosch : Stellenbosch University |
| spellingShingle | Spinal implants Cervical vertebrae -- Surgery Intervertebral disk prostheses Spine -- Surgery Dissertations -- Industrial engineering UCTD Theses -- Industrial engineering Marcantonio, Graziano Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| title | Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| title_full | Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| title_fullStr | Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| title_full_unstemmed | Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| title_short | Development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| title_sort | development of framework for the manufacture of customized titanium cervical cage implants using additive manufacturing |
| topic | Spinal implants Cervical vertebrae -- Surgery Intervertebral disk prostheses Spine -- Surgery Dissertations -- Industrial engineering UCTD Theses -- Industrial engineering |
| url | http://hdl.handle.net/10019.1/86243 |
| work_keys_str_mv | AT marcantoniograziano developmentofframeworkforthemanufactureofcustomizedtitaniumcervicalcageimplantsusingadditivemanufacturing |