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The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome

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Published in:Neuropsychopharmacology Reports
Format: Online Article RSS Article
Published: 2026
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container_title Neuropsychopharmacology Reports
description
discipline_display Psychiatry and Neurology
discipline_facet Psychiatry and Neurology
format Online Article
RSS Article
genre Journal Article
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institution FRELIP
journal_source_facet Neuropsychopharmacology Reports
last_indexed 2026-07-23T03:38:25.527Z
publishDate 2026
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spellingShingle The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
Psychiatry and Neurology
General
Psychiatry and Neurology
sub_discipline_display General
sub_discipline_facet General
subject_display Psychiatry and Neurology
General
Psychiatry and Neurology
subject_facet Psychiatry and Neurology
General
Psychiatry and Neurology
title The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
title_alt El 'freno GABAérgico' sobre el reflejo espinal de defecación: un modelo neurobiológico propuesto que explica la hipomotilidad gastrointestinal inducida por clozapina y benzodiazepinas y el síndrome de Ogilvie
Le « frein GABAergique » sur le réflexe spinal de défécation : un modèle neurobiologique proposé expliquant l'hypomotilité gastro-intestinale et le syndrome d'Ogilvie induits par la clozapine et les benzodiazépines
O “Freio GABAérgico” no Reflexo de Defecação Espinhal: Um Modelo Neurobiológico Proposto Explicando a Hipomotilidade Gastrointestinal Induzida por Clozapina e Benzodiazepínicos e a Síndrome de Ogilvie
title_auth The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
title_es_txt El 'freno GABAérgico' sobre el reflejo espinal de defecación: un modelo neurobiológico propuesto que explica la hipomotilidad gastrointestinal inducida por clozapina y benzodiazepinas y el síndrome de Ogilvie
title_fr_txt Le « frein GABAergique » sur le réflexe spinal de défécation : un modèle neurobiologique proposé expliquant l'hypomotilité gastro-intestinale et le syndrome d'Ogilvie induits par la clozapine et les benzodiazépines
title_full The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
title_fullStr The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
title_full_unstemmed The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
title_pt_txt O “Freio GABAérgico” no Reflexo de Defecação Espinhal: Um Modelo Neurobiológico Proposto Explicando a Hipomotilidade Gastrointestinal Induzida por Clozapina e Benzodiazepínicos e a Síndrome de Ogilvie
title_short The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome
title_sort the “gabaergic brake” on the spinal defecation reflex: a proposed neurobiological model explaining clozapine‐ and benzodiazepine‐induced gastrointestinal hypomotility and ogilvie's syndrome
topic Psychiatry and Neurology
General
Psychiatry and Neurology
url https://onlinelibrary.wiley.com/doi/10.1002/npr2.70157?af=R