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Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors

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Published in:Nucleic Acids Research
Format: Online Article RSS Article
Published: 2026
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container_title Nucleic Acids Research
description
discipline_display Natural Sciences
discipline_facet Natural Sciences
format Online Article
RSS Article
genre Journal Article
id rss_article:45937
institution FRELIP
journal_source_facet Nucleic Acids Research
publishDate 2026
publishDateSort 2026
record_format rss_article
spellingShingle Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
Biology
Natural Sciences — Life Sciences
Natural Sciences
sub_discipline_display Natural Sciences — Life Sciences
sub_discipline_facet Natural Sciences — Life Sciences
subject_display Biology
Natural Sciences — Life Sciences
Natural Sciences
Biology
Natural Sciences — Life Sciences
Natural Sciences
subject_facet Biology
Natural Sciences — Life Sciences
Natural Sciences
title Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
title_auth Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
title_full Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
title_fullStr Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
title_full_unstemmed Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
title_short Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors
title_sort replication protein a protects lagging strand gaps, restricting parp inhibitor-induced synthetic lethality in brca1-deficient tumors
topic Biology
Natural Sciences — Life Sciences
Natural Sciences
url https://academic.oup.com/nar/article/doi/10.1093/nar/gkag396/8663826?rss=1