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Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity

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Published in:PeerJ
Format: Online Article RSS Article
Published: 2026
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container_title PeerJ
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discipline_display Multidisciplinary
discipline_facet Multidisciplinary
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publishDate 2026
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spellingShingle Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
Multidisciplinary
General
Multidisciplinary
sub_discipline_display General
sub_discipline_facet General
subject_display Multidisciplinary
General
Multidisciplinary
Multidisciplinary
General
Multidisciplinary
subject_facet Multidisciplinary
General
Multidisciplinary
title Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
title_auth Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
title_full Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
title_fullStr Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
title_full_unstemmed Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
title_short Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity
title_sort multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing cxcr6+cd8+ t cell anti-tumor activity
topic Multidisciplinary
General
Multidisciplinary
url https://peerj.com/articles/20663