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Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy
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| Published in: | Discover Oncology |
|---|---|
| Format: | Online Article RSS Article |
| Published: |
2026
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| _version_ | 1869844227644456961 |
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| collection | WordPress RSS FRELIP Feed Integration |
| container_title | Discover Oncology |
| description | |
| discipline_display | Endocrinology |
| discipline_facet | Endocrinology |
| format | Online Article RSS Article |
| genre | Journal Article |
| id | rss_article:99668 |
| institution | FRELIP |
| journal_source_facet | Discover Oncology |
| last_indexed | 2026-07-05T03:33:35.377Z |
| publishDate | 2026 |
| publishDateSort | 2026 |
| record_format | rss_article |
| spellingShingle | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy Endocrinology General Endocrinology |
| sub_discipline_display | General |
| sub_discipline_facet | General |
| subject_display | Endocrinology General Endocrinology |
| subject_facet | Endocrinology General Endocrinology |
| title | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| title_alt | El modelado multiómico y de flujo metabólico revela que el 26-hidroxicolesterol derivado de CYP27A1 de macrófagos impulsa la inmunosupresión y la malignidad del cáncer La modélisation multi-omique et du flux métabolique révèle que le 26-hydroxycholestérol dérivé du CYP27A1 des macrophages favorise l'immunosuppression et la malignité du cancer Modelagem multi-ômica e de fluxo metabólico revela que o 26-hidroxicolesterol derivado de CYP27A1 de macrófagos impulsiona a imunossupressão e a malignidade do câncer |
| title_auth | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| title_es_txt | El modelado multiómico y de flujo metabólico revela que el 26-hidroxicolesterol derivado de CYP27A1 de macrófagos impulsa la inmunosupresión y la malignidad del cáncer |
| title_fr_txt | La modélisation multi-omique et du flux métabolique révèle que le 26-hydroxycholestérol dérivé du CYP27A1 des macrophages favorise l'immunosuppression et la malignité du cancer |
| title_full | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| title_fullStr | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| title_full_unstemmed | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| title_pt_txt | Modelagem multi-ômica e de fluxo metabólico revela que o 26-hidroxicolesterol derivado de CYP27A1 de macrófagos impulsiona a imunossupressão e a malignidade do câncer |
| title_short | Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| title_sort | multi-omics and metabolic flux modeling reveal that macrophage cyp27a1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy |
| topic | Endocrinology General Endocrinology |
| url | https://link.springer.com/article/10.1007/s12672-026-05474-3 |