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Replication fidelity in the mircroevolution of mycobacteria
This thesis aimed to elucidate the structure-function relationships determining the differential fidelities of the dnaE1- and dnaE2-encoded mycobacterial PolIIIα subunits under conditions of genotoxic stress. To this end, the role in DnaE1 intrinsic fidelity of highly conserved PHP domain residues...
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| Format: | Thesis |
| Language: | English |
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Division of Medical Biochemistry
2015
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