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Investigation of the role of the DNA-modifying enzyme, activation-induced cytidine deaminase (AID), in cancer
The DNA-editing enzyme, Activation-Induced cytidine Deaminase (AID) is essential for antibody diversification and plays an important role in immunity. AID is specifically expressed in activated B-cells and mutates targeted DNA sites, diversifying the antibody repertoire. Due to its mutagenic nature,...
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| Format: | Thesis |
| Language: | English |
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Division of Clinical Haematology
2016
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