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The application of the homogenisation method to the numerical modelling of cancellous bone

Includes bibliographical references (pages 75-78).

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Main Author: Conway, Damian John
Other Authors: Mitchell, Greg
Format: Thesis
Language:English
Published: Department of Mechanical Engineering 2016
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access_status_str Open Access
author Conway, Damian John
author2 Mitchell, Greg
author_browse Conway, Damian John
Mitchell, Greg
author_facet Mitchell, Greg
Conway, Damian John
author_sort Conway, Damian John
collection Thesis
description Includes bibliographical references (pages 75-78).
format Thesis
id oai:open.uct.ac.za:11427/20459
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:23.204Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2016
publishDateRange 2016
publishDateSort 2016
publisher Department of Mechanical Engineering
publisherStr Department of Mechanical Engineering
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/20459 The application of the homogenisation method to the numerical modelling of cancellous bone Conway, Damian John Mitchell, Greg Spirakis, Thanos Mechanical Engineering Includes bibliographical references (pages 75-78). This thesis reports on an investigation into the viability of developing idealised numerical models of cancellous bone in order to make reasonable predictions about its macro- and microstructural mechanical behaviour using the homogenisation method. In total joint replacement, cancellous bone (the soft porous bone which lies below the articular surfaces at weight-bearing joints) provides the medium for the transfer of loads from the artificial component, or prosthesis to the hard, outer cortical bone. Although total joint replacement is usually a successful operation - providing relief from pain and often considerably improved joint function - loosening of the metal components remains a major obstacle to the long-term success of these operations. In the ongoing work to develop joints which are less susceptible to loosening, it has become necessary to study the micromechanics of cancellous bone in order to predict its response to the changing stress environments brought about by the inserted prostheses. Biomechanical engineers have used finite element analysis extensively in the analysis of reconstructed joints. However, owing to the prohibitively high computational costs associated with the microstructural modelling of cancellous bone, it is generally modelled simply as a homogeneous, isotropic material. It is not possible to accurately predict the mechanical response of cancellous bone to various implant conditions under this simplistic modelling assumption. Thus, alternative methods are being sought which will allow for more realistic modelling of cancellous bone. The homogenisation method is one such alternative. This method makes it possible to uncouple the analysis of some problem involving a composite material into an apparent global analysis and a local microstructural analysis. The apparent material properties of the periodically repeating composite microstructure are calculated, taking into account the structural heterogeneities of the composite. These properties are then used in the global analysis where the composite is treated as a continuum. The apparent global-level results are subsequently postprocessed to obtain the microstructural behaviour in any local regions of interest. The main aim of this research project was to investigate the applicability of the homogenisation method to the modelling of cancellous bone. The first part of this work involved an extensive literature study on the architecture and micromechanics of cancellous bone to investigate whether cancellous bone can indeed be modelled as an idealised composite material with a periodically repeating microstructure. The outcome of this investigation revealed that the structure and behaviour of cancellous bone is highly variable - depending on the patient, anatomic location and the level of density. However, certain regions of cancellous bone do have typical repeating architectures which have a major influence on the apparent mechanical behaviour of the bone. Thus it has been concluded that these specific regions of cancellous bone can be modelled by idealised structures, provided the observed microstructures and predominant deformations modes are well characterised in the models. 2016-07-19T14:21:43Z 2016-07-19T14:21:43Z 1995 Master Thesis Masters MSc http://hdl.handle.net/11427/20459 eng application/pdf Department of Mechanical Engineering Faculty of Engineering and the Built Environment University of Cape Town
spellingShingle Mechanical Engineering
Conway, Damian John
The application of the homogenisation method to the numerical modelling of cancellous bone
thesis_degree_str Master's
title The application of the homogenisation method to the numerical modelling of cancellous bone
title_full The application of the homogenisation method to the numerical modelling of cancellous bone
title_fullStr The application of the homogenisation method to the numerical modelling of cancellous bone
title_full_unstemmed The application of the homogenisation method to the numerical modelling of cancellous bone
title_short The application of the homogenisation method to the numerical modelling of cancellous bone
title_sort application of the homogenisation method to the numerical modelling of cancellous bone
topic Mechanical Engineering
url http://hdl.handle.net/11427/20459
work_keys_str_mv AT conwaydamianjohn theapplicationofthehomogenisationmethodtothenumericalmodellingofcancellousbone
AT conwaydamianjohn applicationofthehomogenisationmethodtothenumericalmodellingofcancellousbone