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Immunogenic assessment of plant-produced Human papillomavirus type 16 chimaeric L1:L2 virus-like particles and the production of an encapsidated therapeutic DNA vaccine candidate

Cervical cancer caused by infection with Human papillomavirus (HPV) is the 4th most common cancer in women globally, and results in an estimated 266 000 deaths every year. Current vaccines are based on the immunodominant L1 major capsid protein, which assembles into virus-like particles (VLPs) that...

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Main Author: Chabeda, Eva Aleyo
Other Authors: Hitzeroth, Inga I
Format: Thesis
Language:English
Published: Department of Molecular and Cell Biology 2018
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