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Synthesis, physicochemical and biological evaluation of N-dealkylated metabolites of antimalarial pyrido[1,2-a]benzimidazoles and related compounds containing a Mannich base side-chain

Malaria is one of the leading causes of deaths worldwide. Despite strategic implementations aimed at decreasing mortality and morbidity rates in recent decades, this plasmodial disease continues to impact public health and the economies of developing countries. Furthermore, the emergence of resistan...

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Bibliographic Details
Main Author: Ferger, Richard
Other Authors: Chibale, Kelly
Format: Thesis
Language:English
Published: Department of Chemistry 2020
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