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Design, synthesis, and structure-activity relationship studies of dual Plasmodium falciparum phosphatidylinositol 4-kinase and cGMP-dependent protein kinase inhibitors

Malaria is a life-threatening disease caused by protists in the genus Plasmodium and transmitted by the female Anopheles mosquito. Amongst five species which infect humans, Plasmodium falciparum (Pf) causes the severest form of the disease. Although significant efforts have been made to reduce the o...

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Bibliographic Details
Main Author: Gachuhi, Samuel Njoroge
Other Authors: Chibale, Kelly
Format: Thesis
Language:English
Published: Department of Chemistry 2022
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