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Statistical modelling to determine the influence of vaccine dose and prior Mycobacterium tuberculosis exposure on antigen-specific T cell responses
This dissertation investigates the effects of two subunit vaccines H1:IC31 and H56:IC31 as well as prior M.tb sensitization on the immune responses of three cohorts of South African adolescents and adults. The primary outcomes are frequencies of antigen-specific CD4 T cells expressing different comb...
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| Format: | Thesis |
| Language: | English ENG |
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Department of Statistical Sciences
2025
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