Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Two New phytoecdysteroids from sphenocentrum jollyanum pierre root
The crude methanol extract of Sphenocentrum jollyanum root exhibited 98% and 80% antimicrobial activity against Aspergillus fumigatus Pinh and Vancomycin resistant enterococcus (VRE) at a concentration of 200 μg/mL, with ICso 11.45 and 12.95 μg/mL, respectively. The ethyl acetate fraction of methano...
Saved in:
| Format: | Article |
|---|---|
| Published: |
2019
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| Summary: | The crude methanol extract of Sphenocentrum jollyanum root exhibited 98% and 80% antimicrobial activity against Aspergillus fumigatus Pinh and Vancomycin resistant enterococcus (VRE) at a concentration of 200 μg/mL, with ICso 11.45 and 12.95 μg/mL, respectively. The ethyl acetate fraction of methanol extract showed in-vitro antimicrobial activity against A. fumigatus Pinh at 83% with ICso of <8 μg/mL. The phytochemical investigation of ethyl acetate fraction yielded six compounds, which were identified by their NMR, IR and MS spectral analyses as two new phytoecdysteroidal glycosides Sphenocentroside A (1), and NUSART Sphenocentroside B (2), and four known phytoecdysteroids: polypodoaurein (3), polypodine B (4), ecdysterone (5), and 20, 26-dihydroxyecdysone (6). |
|---|