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Formulation optimization of floating microbeads containingmodified Chinese yam starch using factorial design.
Controlled release floating metformin hydrochloride microbeads were prepared and optimized using a blend of varying concentrations of freeze-dried pregelatinized Chinese yam starch (Dioscorea oppositifolia L) and sodium alginate. Floating microbeads were prepared by the ionotropic gelation method us...
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2012-03
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