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Optimization of formulations of metoprolol succinate tablets containing ofada rice starch acetate as tablet matrix for sustained release using response surface methodology
Background: Release-retarding polymers in matrix tablets play a vital role in controlling drug release from tablets. Objectives: To prepare metoprolol succinate tablets by direct compression using Ofada rice (Oryza glaberrima Steud) starch acetate, degree of substitution (DS) 2.22, as a matrix for...
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2016
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